vibrio

Question 1

Agent of Cholera “Asiatic/Epidemic Cholera”

Answer 1

Vibrio cholerae

Question 2

Prevalent in India

Answer 2

Ogawa (AB)

Question 3

Prevalent in Philippines

Answer 3

Inaba (AC)

Question 4

Hikojima (ABC)

Answer 4

Japan

Question 5

V. cholerae produces choleragen (“cholera toxin”) that promotes prolonged hypersecretion of water & electrolytes resulting in _____________ which leads to severe dehydration & death.

Answer 5

profuse watery diarrhea

Question 6

Effect of action of Choleragen:

Answer 6

rice watery stool

Question 7

reagent in string test, positive result viscous string

Answer 7

0.5% sodium deoxycholate

Question 8

incubation period of vibrio cholerae

Answer 8

2-3 days

Question 9

Clinical manifestations of _______
eyes and cheeks are sunken
▪ diminished skin turgor
▪ washerwoman’s hands

Answer 9

Vibrio cholerae

Question 10

Profuse watery diarrhea, as much as ____

Answer 10

1 l/hr

Question 11

• Loss of _____ liters of fluid /day results in Hypovolemia
  and acidosis to shock and eventual death

Answer 11

15-20

Question 12

fluid and mucus flecks; contain epithelial cells and
vibrios [cholera -10 -30x defecation per day]

Answer 12

Rice watery stool

Question 13

treatment to to decrease number of organisms
multiplying in the intestines

Answer 13

tetracycline

Question 14

treatment that shortens the duration of diarrhea and
magnitude of fluid loss
eg; doxycycline, azithromycin, ciprofloxacin

Answer 14

antibiotics

Question 15

Second most common Vibrio spp. implicated in
gastroenteritis
* First recognized as a food pathogen in Japan in 1950

Answer 15

vibrio parahaemolyticus

Question 16

primary cause of “summer diarrhea”

Answer 16

vibrio parahaemolyticus

Question 17

clinical manifestation of v. parahaemolyticus

Answer 17

watery diarrhea

Question 18

pathogenesis of v. parahaemolyticus

Answer 18

kanagawa phenomenon

Question 19

Possible association with the production of hemolysin
and virulence potential known as ______

Answer 19

Kanagawa
phenomenon

Question 20

in V. parahaemolyticus, Most clinical isolates or strains produce a heat-stable hemolysin that are able to lyse human RBC’s in a special high salt medium known as ______________

Answer 20

Wagatsuma’s agar.

Question 21

After cholera, ______ is considered as the second
most serious type of Vibrio-associated infections

Answer 21

Vibrio vulnificus

Question 22

Of the 4 major members of Vibrio spp. Likely to be
encountered in the clinical laboratory, it is the least pathogenic for humans and is least likely to be encountered

Answer 22

Vibrio alginolyticus

Question 23

a strict halophile-requires at least ____ and can tolerate up to 10% NaCI

Answer 23

3% Sodium Chloride