VHB Flashcards

1
Q

VHB: type d’acide nucléique

A
  • ADN
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2
Q

VHB: contamination

A
  • sexuelle, materno-foetale +++
  • toxicomanie IV ++
  • transfusion +
  • +- féco orale
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3
Q

VHB: prévention

A
  • déclaration obligatoire en cas d’hépatite B aigue symptomatique
  • vaccination > 95% efficace
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4
Q

VHB: incubation

A
  • 80 ( 30-120)
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5
Q

VHB forme aigue: D

A
  • IgM anti-HBc
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6
Q

VHB forme aigue: symptomatique

A
  • 10%
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7
Q

VHB forme aigue: T

A
  • si fulminante
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8
Q

VHB forme aigue: fulminante

A
  • 0,1 - 1%
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9
Q

VHB forme chronique: %

A
  • 10% adulte

- 90% nouveau-né

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10
Q

VHB forme chronique: D

A
  • Ag HBs à 6 mois d’intervalle

Affirmé à 2 AgHBs+ à 6 mois d’intervalle

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11
Q

VHB forme chronique: T

A
  • IFN ou analogue (nucléosidique ou nucléotidique)
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12
Q

VHB forme chronique: cirrhose

A
  • 20% après 20 ans
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13
Q

VHB: guérison

A
  • AC anti-HBs
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14
Q

VHB: co-infection VIH

A
  • +
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15
Q

VHB: info

A
  • en cas de forme chronique infective -> augmentation du risque de carcinome hepatocellulaire et cirrhose post-nécrotique
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