Vet Pharmacy Flashcards
1
Q
Differences to Consider When Answering Questions
A
• Species differences
- Pharmacokinetics/Pharmacodynamics (dosing challenges)
- Behavior traits, husbandry, grooming habits, palatability
• Cost of Therapy
• Compliance
• Role of animal in household
- Companion vs. Food animal vs. Service animal vs. Breeding stock vs. Performance animal
• Toxicities
2
Q
Acetaminophen (OTC)
A
- Contraindicated in cats and ferrets
- Lack ability to metabolize in liver via glucuronidation
- Hepatotoxicity in dogs
- Methemoglobinemia, hematuria, and icterus occur
3
Q
NSAIDs and ASA (OTC)
A
- Dose-dependent toxicity in dogs and cats
- Much longer half-lives
- Vomiting, GI ulceration, hematemesis, melena, Heinz body anemia (cats), metabolic acidosis, hyperthermia, renal and liver damage
4
Q
Levothyroxine and dogs (Rx)
A
- Doses for dogs can be 10x or more a human dose
- Shorter half-life, lower oral bioavailablity
- Human tablets range: 25mcg-300mcg
- Veterinary tablets: 200mcg-1000mcg
5
Q
Animals and Pharmacists
A
- SID
- Prescription abbreviation commonly implicated in errors
- Persistent use in veterinary practices
What does it mean?
• semel in die
• Once a day
6
Q
Top References
A
- Plumb’s Veterinary Drug Handbook
- Exotic Animal Formulary
- Merck Veterinary Manual
- Compendium of Veterinary Products
- Animal Drugs @ FDA
- Daily Med
