Vestibular Systems Flashcards
Which structures in the body are responsible for angular rotation of the head?
3 Semi-circular canals
Which structures in the body sense the acceleration of the head and the strength of gravity?
Otolith organs
What are the 2 otolith organs?
Saccule
Utricle
What are 6 main functions of the vestibular system?
Perception of movement in space + tilt with respect to gravity
Provide reflex balance reactions to sudden instability of gait/posture (vestibulo-spinal reflexes)
Preserve visual acuity during head movement (vestibulo-ocular reflexes)
Assist in control of HR + BP during rapid up-down tilts
Assist synchronisation of respiration with body orientation
Provide a reference for absolute motion in space
Define vertigo.
False perception of movement in space
Define vestibular ataxia
Instability of gait or posture
What happens to the ability of the brain to stabilise the eyes in unilateral vestibular lesions?
Vestibular nystagmus
Eyes start moving in the direction of the lesion
Intermittent “resetting” of eye position with fast saccades
What happens to the ability of the brain to stabilise the eyes in bilateral vestibular lesions?
Oscillopsia
Everything appears to be shaking – the ability to stabilise the eyes is lost
What are some other consequences of vestibular loss?
Slight impairment of orthostatic control
Severe nausea and vomiting
Loss of coordination on directional reorientation, motion intolerance, oversensitivity to visual motion in the environment
Describe the saccule
Bed of sensory cells situated in inner ear
Orientated in vertical plane
Detect linear acceleration + head tilt in vertical plane
Describe the structure of otolith hair cells
Have an overlaying layer of Otoconia
Project normal to the plane of the saccule
Have 1 kinocilia per cell, the rest are stereocillia
What does the hair cell fibre synapse with and where does it project?
It synapses with a primary neurone dendrite (cell body in Scarpa’s ganglion)
They project to the vestibular nuclei in the brainstem
What stimulates hair cells?
In Otoliths: deflection by forces of inertial resistance to acceleration
In Semi-circular Canals: endolymphatic fluid rotation
Describe how the hair cell receptor potential can be changed.
Depolarisation = movement towards the kinocilium Hyperpolarisation = movement away from the kinocilium
Describe how ganglion cell discharge can be changed.
Towards the kinocilium = increased firing frequency
Away from the kinocilium = decreased firing frequency
Describe the sensitivities of the saccule
Directional sensitivities in all combinations of vertical + antero-posterior directions
Describe the structure of the utricle and its sensitivities.
Oriented horizontally with the hair cells projecting vertically
Directional sensitivities in all combinations of lateral + antero-posterior directions