Vestibular schwannoma Flashcards

1
Q

What is a vestibular schwannoma (AKA acoustic neuroma)?

A

A benign tumour of the Schwann cells surrounding the auditory nerve (vestibulocochlear nerve) that innervates the inner ear.

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2
Q

Which cranial nerve is the vestibulocochlear nerve?

A

CN VIII

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3
Q

Which portion of the vestibulocochlear nerve does a vestibular schwannoma predominantly affect?

A

Vestibular portion - hearing loss, tinnitus & balance issues.

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4
Q

What cells does a VS arise from?

A

Schwann cells

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5
Q

Acoustic neuromas are usually unilateral.

What condition are bilateral vestibular schwannomas seen in?

A

Neurofibromatosis type 2

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6
Q

Where are Schwann cells found?

A

PNS

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7
Q

What is role of Schwann cells?

A

Provide myelin sheath around neurones

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8
Q

Where in the brain do VS occur?

A

At the cerebellopontine angle (sometimes referred to as cerebellopontine angle tumours).

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9
Q

Typical age of presentation of VS?

A

40-60 y/o

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10
Q

What clinical features are seen in VS?

A

1) Unilateral sensorineural hearing loss (often the first symptom)

2) Unilateral tinnitus

3) Dizziness or imbalance

4) A sensation of fullness in the ear

5) Facial nerve palsy (if the tumour grows large enough to compress the facial nerve)

6) Headache, N&V (increased intracranial pressure in large tumours)

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11
Q

What is the most common presenting symptom of VS?

A

Unilateral sensorineural hearing loss

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12
Q

Who should patients with a suspected vestibular schwannoma be referred urgently to?

A

ENT

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13
Q

Investigations in VS?

A

1) Audiometry

2) Brain imaging: MRI

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14
Q

Role of audiometry in VS?

A

Used to assess hearing loss. There will be a sensorineural pattern of hearing loss.

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15
Q

What is the gold standard imaging for diagnosing VS?

A

MRI

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16
Q

Mx of VS?

A

1) Observation (small, asymptomatic tumours with slow growth rates)

2) Surgery to remove the tumour (partial or total removal)

3) Radiotherapy to reduce the growth

17
Q

What are 2 notable risks with treatment of VS?

A

1) Vestibulocochlear nerve injury, with permanent hearing loss or dizziness

2) Facial nerve injury, with facial weakness

18
Q
A