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PBO > Vestibular And Auditory Ototoxicity > Flashcards

Vestibular And Auditory Ototoxicity Flashcards

1
Q

First aminoglycoside still in use

A

Streptomycin

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2
Q

Aminoglycosides are first line therapy for what conditions (3)

A

Neonatal sepsis, TB, pseudomonal infection

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3
Q

Usual ototox8c dose for Streptomycin (g/day, number of days)

A

1g/day, 35-90 days

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4
Q

Possible ototoxic metabolite of streptomycin

A

Streptidine

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5
Q

Reason why inner hair cells are relatively resistant to ototoxicity

A

Increased antioxidant (glutathione) concentration in IHCs and in the apical turn OHCs

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6
Q

Definition of drug related hearing loss (how many dbs and conditions)

A

20 db in 2 adjacent frequencies

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PBO (6 decks)

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