Vertebral fractures Flashcards

1
Q

In what percentage of patients with vertebral luxation/fracture are concurrent injuries present?

A

45-83%.

Thoracic trauma: 15-25%.
Abdominal trauma: 6-15%.
Pelvic fractures: 14-48%.

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2
Q

In what percentage of cases with vertebral luxation/subluxation are multiple fractures/luxations present?

A

15-20%. Dogs weighing <15kg more predisposed to multiple fractures.

Survey radiographs of the entire vertebral column are recommended to rule out multiple injuries.

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3
Q

Is absent nociception associated with a worse prognosis for patients with IVDH or vertebral fracture?

A

Vertebral fracture, luxation or subluxation. Only 12% of dogs in one study regained ambulation.

80-90% of cases with intact nociception can achieve good outcomes.

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4
Q

What imaging modalities might be used for work-up of vertebral luxation/fracture?

A
  1. Radiography.
  2. Myelography.
  3. CT: allows for the most accurate determination of vertebral canal stability.
  4. MRI: provides useful information regarding the paraspinal soft tissues, intervertebral discs, and ligamentous support structures (which provide vertebral stability), as well spinal cord injury.
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5
Q

What is associated with a negative outcome in dogs with vertebral fracture/luxation based on radiographs?

A

Degree of dislocation. 100% dislocation and absence of nociception warrants a grave prognosis.

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6
Q

What parts of the vertebral canal is radiography particularly poor at evaluation?

A

The dorsal and middle compartments. Also lacks sensitivity for detection of fracture fragments within the vertebral canal or spinal cord compression.

Overall sensitivity only 72%.

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7
Q

What are the anatomic classifications in the three compartment model of vertebral stability?

A

Dorsal, middle and ventral. If more than one of these compartments is compromised the vertebral column is considered unstable and surgical intervention is recommended

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8
Q

What comprises the dorsal, middle, and ventral compartments of the vertebral column?

A

Dorsal: spinous processes, vertebral laminae, articular processes, vertebral pedicles, and dorsal ligamentous complex (supraspinous ligament, interspinous ligament, joint capsule of the zygapophyseal joints, and ligamentum flavum).

Middle: dorsal longitudinal ligament, the dorsal portion of the annulus fibrosus, and the dorsal portion of the vertebral body.

Ventral: remainder of the vertebral body, the lateral and ventral portions of the annulus fibrosus, the nucleus pulposus, and the ventral longitudinal ligament

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9
Q

What are the three principle contributors to vertebral instability as per the simpler classification model of vertebral stability?

A

Intervertebral disc: primarily responsible for rotational stability, also involved in lateral bending. Vertebral body may provide some buttressing in bending if still intact with disc injury.

Vertebral body: bending forces and axial compression. Fracture of the vertebral body alone is likely to be very unstable.

Articular process: resists all forces. Isolated fracture of one or both articular process may not result in vertebral instability.

Injury to more than one of these compartments should be considered unstable.

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10
Q

Describe a treatment algorithm for vertebral fractures/luxations

A
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11
Q

Has the use of corticosteroids been shown to improve outcomes following vertebral fracture/luxation?

A

No.

Their proposed use has been related to their anticipated function as an antioxidant, which may help to reduce secondary spinal cord injury.

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12
Q

What are non-surgical treatment options for vertebral luxation/sublxuation?

A

Cage rest +/- external coaptation.

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13
Q

Which patients are the best candidates for external coaptation?

A

Small patients with minimal neurologic dysfunction, intact ventral buttress and lack of concurrent thoracic, abdominal or pelvic injuries

External coaptation is unlikely to realign the vertebral column.

Lesions in the lumbosacral vertebral column might be most forgiving.

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14
Q

When external coaptation is used for treatment of vertebral fracture/luxation what is the extent of splint material that is required for stability?

A

Lumbar: should include whole pelvis
Cervical: should go to level of eyes (to stabilize the atlanto-occiptal joint) and midthorax.

Ideally maintained for a minimum of 4 weeks.

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15
Q

When is surgery indicated for a patient with vertebral luxation/subluxation?

A
  1. Paretic animals with intact nociception.
  2. Worsening neurologic status or unstable fractures.
  3. Spinal cord compression.
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16
Q

What surgical techniques are primarily used for TL vertebral fracture/luxation stabilization?

A
  1. Pins PMMA.
  2. Ex-fix.
  3. Locking plates (SOP most frequent, lateral LCP described).

These techniques can all be used with compromised integrity of two or more vertebral column compartments.

Additional techniques include:
4. Spinal process plating.
5. Spinal stapling.

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17
Q

What are the main vascular structures that are at risk during pin placement for vertebral fracture stabilization?

A

The azygous lies just ventral to the right thoracic vertebral column (often within 1mm of vertebral body). Aorta, pleura and lung are also in close proximity to thoracic vertebrae.

In the lumbar vertebrae these structures are somewhat protected by the presence of the hypaxial muscles.

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18
Q

What is the pin entry point for pin and PMMA constructs?

A

Lumbar: between the base of the transverse process and the accessory process.

Thoracic: level of the accessory process or tubercle of the rib.

Pins should be directed cranially in the cranial vertebra, and caudally in the caudal vertebra to engage the end plates.

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19
Q

What are the ideal pin insertion angles for TL vertebral stabilization?

A

30-60 degrees.

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20
Q

What diameter should pins be limited to for TL vertebral stabilization?

A

20-25% of the diameter of the vertebral body

21
Q

If bleeding is encountered during drilling of the pilot hole for pin placement in TL vertebral stabilization what structures might be responsible?

A

Might be penetration of vertebral venous plexus, or damage to the centrally located basivertebral veins

22
Q

How many pins are required to provide adequate stabilization of a TL vertebral fracture/luxation?

A

4 pins and PMMA shown to have equivocal stiffness in extension, flexion and rotation as the intact vertebral column in biomechanical testing

23
Q

What compartment does spinous process instrumentation for the treatment of TL fractures/luxations not stabilize?

A

The ventral compartment

24
Q

What types of ESF can be used for vertebral fracture/luxation fixation?

A

Type 1a or 1b.

Type 1b ESF spanned with spinal arches is as strong as a 8 pin PMMA complex.

25
Q

What are the advantages/disadvantages of ESF fixation of spinal fracture/subluxation?

A

Advantages: reduction can be adjusted post-operative, removal of the implant following healing reduces the risk of delayed implant infection.

Disadvantages: pin care and maintenance, risk of inflammation/infection, traumatic deinstrumentation by the patient.

26
Q

What are the most common implants used for plating of vertebral fracture/luxation?

A

SOP plate: typically applied bilaterally, at similar angles as those described for pin/PMMA fixation. Recommend at least 3 screws per vertebra total (between the two constructs). Engagement of the far cortex is not essential for stability.

LCP: can be applied laterally to the vertebral body to allow for application of compression. Not as strong as a pin/PMMA construct but still stronger than the intact vertebral column.

Due to their close proximity to the intervertebral foramina may cause impingement on the spinal nerves.

27
Q

What are options for stabilization of vertebral fractures/luxations using the spinous processes?

A

1) Bilateral spinal plating using Auburn metal plates, or Lubra plastic plates.
2) Spinal stapling.

28
Q

Do spinous process instrumentation techniques stabilize ventral compartment injuries?

A

No.

Might be less costly and technically easier, however.

29
Q

What are some disadvantages of spinous process instrumentation techniques for spinal fracture stabilization?

A
  1. Requires immobilization of at least 5-6 vertebrae.
  2. Requires intact spinous processes.
  3. Does not stabilize a highly unstable articulation or fracture.
  4. Prone to failure (spinous processes are weak leading to device pull-out, spinous process fracture, or ischemic necrosis of the spinous processes).
30
Q

How many spinous processes need to be spanned for spinous process instrumentation of the TL spine?

A

5-6

31
Q

When is hemilaminectomy indicated in conjunction with vertebral fixation for treatment of vertebral fracture/luxation?

A

If there is evidence of compression secondary to an extradural mass (hemorrhage, bone, IVD).

Hemilaminectomy preferred over dorsal laminectomy due to less destabilization. Pediculectomy or mini-hemi may be even better.

32
Q

What is the most common site of cervical vertebral fracture or luxation?

A

C1 and C2 (50-70% of cervical fractures). May be due to static-kinetic relationship between relatively stable caudal cervical column and dynamic C1/C2/skull

33
Q

What are the most common stabilization techniques for cervical fractures/luxation?

A

Pins PMMA most common and versatile. Locking plates also described.

34
Q

What are the main differences between cervical and thoracolumbar stabilization?

A

Ventral approach for cervical stabilization. Cervical pedicles are narrow and transverse processes have transverse foramina that contain the vertebral arteries, veins and nerves. This makes safe passage of implants challenging. Pin insertion angles are varied and should be determined based off CT pre-op, although angles of 20-35 degrees have been described.

35
Q

Why is the C7 vertebra slightly more forgiving than other cervical vertebrae for pin placement?

A

Lacks transverse foramina, therefore there is less concern of damage to the vertebral artery, vein or nerve.

36
Q

How does fixation of the fractures of the C2 vertebra differ from fractures of the other cervical vertebrae?

A

The C2 vertebra has a thin body with little purchase for implants. Ideally ventral fractures should be stabilized using the addition of implants that cross the C1/C2 joint space (angled 40 degrees in the transverse plane toward the alar notch, and 20-30 degrees in the sagittal plane).

Implant placement in the body of C3 should be considered for caudal C2 vertebral body fractures.

37
Q

What are some advantages of locking plate over pin/PMMA fixation for cervical fracture fixation?

A

Monocortical screw placement may reduce risk of iatrogenic trauma. Less potential for heat generation, tissue damage, and hypersensitivity reactions. Removal is much more straight forward if required.

38
Q

What are some locking plate systems described for cervical fracture fixation?

A
  1. Cervical spine locking plate (CSLP, Synthes –humans)
  2. UniLock (Synthes –human maxillofacial reconstruction plate)
  3. String of Pearls (SOP –Orthomed)
  4. LCP plate (Synthes)
39
Q

Why are lumbosacral fractures/luxations associated with a better prognosis than more cranial lesions?

A

The spinal cord typically ends at L6 making the L7 vertebral foramen more spacious for the nerve roots. Nerve roots are also more tolerant and recovery better from concussive damage.

40
Q

What is the most common imaging presentation of LS fracture/luxation?

A

Cranioventral sacral displacement with small caudoventral wedge fracture of the L7 body

41
Q

What are neurologic signs consistent with injury to the lumbosacral joint?

A

Sensory and motor deficits in the sciatic nerve, urinary and fecal incontinence, perineal and tail hypalgesia/anesthesia, absent tail and external anal sphincter tone.

Severe neurologic deficits carry a guarded prognosis for functional return.

42
Q

What surgical techniques are most commonly used for repair of lumbosacral fractures/luxations?

A
  1. Pins/PMMA.
  2. Locking plates (bilateral with 3 screws each in L7 and sacrum).
  3. Pedicle screw system (as described for lumbosacral stenosis).

Implants can span the L7 vertebrae and engage the L6 vertebra if required for complex fractures.

43
Q

Why is placement of implants relatively easier in the L7 vertebra than other vertebral sites?

A

Relatively thicker pedicles.

44
Q

What are the landmarks for insertion of implants in L7 and the sacrum during repair of fracture/luxation?

A

L7: just caudal to the cranial articular process, directed cranially and medially.

Sacrum: just caudal to the cranial articular process, directed caudally and laterally. Should engage the long axis of the body of the ilium (via the SI joint) for increased purchase and security.

45
Q

What are some complications associated with vertebral luxation/fracture stabilization?

A
  1. Vascular complications.
  2. Pneumothorax.
  3. Inadequate reduction/penetration of the vertebral canal.
  4. Infection.
  5. Iatrogenic damage to neurovascular structures.
  6. Implant migration, non-union, mal-union, excessive callus formation.
46
Q

In dogs with cervical vertebral luxation/fracture how many times greater chance of a functional recovery do dogs have who present ambulatory compared to non-ambulatory?

A

13 times greater chance

47
Q

Is the prognosis for vertebral luxations/fractures considered poor or good when nociception is intact?

A

Generally good. Typically best for cases of lumbosacral luxation/fracture.

Cervical: 70% return to function.
Thoracolumbar: 80-100% return to function.
Lumbosacral: excellent prognosis often even without surgery. Severe neurologic deficits are uncommon.

48
Q

What technique was used by Bitterli 2022 in VCOT for successful repair of thoracolumbar spinal fractures and luxations? What were the most common complications?

A

Unilateral uniplanar percutaneously placed (under fluoroscopic guidance) ESF (type 1a).

Erythema, exudation and pin loosening were the most common complications.