Verification and RM

Question 1

Validation

Verification

Answer 1

Confirmation by examination and provision of evidence that the particular requirements for a specific intended usehave been met

Question 2

Robustness

Answer 2

Insensitivity against changes of known operational paramaeters

Question 3

Fit for purpose evaluation

Answer 3

What’s the question
What analytical technique
What’s the analyte

Question 4

What is type 1 error and type 2?

Answer 4

False positive result

Null hypo rejected even though it’s true

Question 5

The lower the p value the lower the what?

Lower the statistical power, the lower the what

Answer 5

False positive

False negative

Question 6

What to look for in cert?

Answer 6

Analyte and matrix
Analytical method, traceability to SI
Uncertainty and coverage factor

Question 7

Who produces CRM?

Answer 7

National institutes of standard and tech

Institute of reference material and measurement

NMI

Private companies

Question 8

What are the types of reference materials?

Answer 8

Reference mat:
Primary, secondary, control samples

Measurement standards
Working, reference, National, international

Question 9

How to produce CRM

Answer 9

Base materials
Homogenize
Stability
Assignment of reference value
Uncertainty statement

Question 10

How do u use CRM?

Answer 10

Avoid contamination,
Follow instructions
Choose according to what u need it for

Question 11

How do u choose CRM?

Answer 11

Best possible match
Correct uncert range
ISO accreditation 
Traceability
Cost

Question 12

What is a RM?

Answer 12

Homogenous and stable. Fit for purpose

Question 13

What is a CRM?

Answer 13

RM with a certificate issued by
Specified property values 
Uncertainty
Traceability
Using valid procedures