Ventricular diastolic function Flashcards

1
Q

What does diastolic dysfunction frequently occur before?

A

systolic dysfunction

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2
Q

When is diastole on the ECG?

A

between the end of the T wave and the peak of the R wave

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3
Q

What does the duration of diastasis depend on?

A

HR

is longer is a slow HR and can be absent with a fast HR

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4
Q

List the parameters of diastolic function

A
  • ventricular relaxation
  • myocardial/chamber compliance
  • filling pressures (can change based on pathology)

-also: elastic recoil of ventricle, and pericardial constraint

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5
Q

Describe abnormal ventricular relaxation

A

prolonged IVRT
slower rate of decline in ventricular pressure
reduced early peak filling rate

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6
Q

What factors can affect IVRT?

A

internal or external loading forces

inactivation of myocardial contraction

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7
Q

What does a more compliant ventricle allow?

A

allows more blood volume (vise versa)

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8
Q

How can compliance be defined?

A

ratio of change in volume to change in pressure

stiffness is the inverse

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9
Q

What are some factors that affect peak early diastolic filling rate?

A

changes in preload that affect the initial pressure difference between the ventricles and the atria (increased with volume loading, vise versa)
change in transmitral flow rate
change in atrial pressures

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10
Q

What are some factors than can affect late diastolic filling?

A

cardiac rhythm and rate
atrial contractile function and timing of contraction
ventricular end diastolic pressures
ventricular diastolic function

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11
Q

What do elevations in ventricular diastolic pressures affect?

(pressures where?)

A

pressures in the atria

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12
Q

What affects RA filling patterns?

What results in an absent atrial reversal?

A

respiratory variations

nonsinus cardiac rhythm

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13
Q

What do patients with pericardial disease have in RV and LV diastolic filling?

A

exaggerated respiratory phases

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14
Q

What is the normal velocity range for the mitral E wave?

A velocity?

A

.6-1.3m/s

.2-.7m/s

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15
Q

In the mitral valve waveform, what is a normal deceleration slope? deceleration time?

A

4.3-6.7m/s

140-200ms

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16
Q

What does TDI measure?

What does the E wave and A wave correspond with?

A

the velocity of longitudinal myocardial lengthening in diastole and shortening in systole

E: early rapid filling
A: atrial contraction

17
Q

What is the abnormal cut off for TDI septal E’ velocity? Lateral E’?
Average E/E’ ratio

A

<7cm/s
<10cm/s

> 14

18
Q

What is a normal IVRT value?

What results in a prolonged IVRT? Short IVRT?

A

50-100ms

impaired relaxation
decreased compliance and elevated filling pressures

19
Q

Describe how the mitral valve waveform changes as a patient ages?

A

with aging: E velocity decreases, A increases

equalization: happens approx. at age 50
reversal: normal in patients older than 50yo

20
Q

What is the change in LA flow with aging?

A

reduction in diastolic filling phase and compensatory increase in systolic filling phase
there is more prominent atrial reversal in patients older than 50