Venous Return and its Control Flashcards

1
Q

if we increase the EDV through increased VR we ____ the SV

A

increase

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2
Q

the heart is not working at optimum fibre length at rest . what does this mean for the heart?

A

it has potential to do more work

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3
Q

what are 4 examples of factors that increase venous return?

A
  1. increased venomotor tone
  2. increased skeletal muscle ‘pump’
  3. increased respiratory pump
  4. increased blood volume
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4
Q

what does an increase in VR do?

A

increases atrial pressure which ^ EDV which ^ SV

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5
Q

what is the venomotor tone?

A

Venous smooth muscles are supplied with sympathetic nerve fibres.
Stimulation gives venous constriction
On account of venous valves, blood driven to right atrium

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6
Q

what does increased VENOmotor tone do?

A

INCREASES VENOUS RETURN, SV & MAP

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7
Q

what does increased VASOmotor tone do?

A

INCREASES TPR & MAP

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8
Q

what is the skeletal muscle pump?

A

Large veins in limbs lie between skeletal muscles

Contraction of muscles aids venous return

One-way venous valves allow blood to move forward towards the heart

Muscle Activity increases VENOUS RETURN to heart

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9
Q

what happens to the sympathetic nerve activity during exercise

A

increases

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10
Q

what happens to HR and SV during exercise

A

increase. this increases CO

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11
Q

what happens to sympathetic vasomotor nerve flow to kidneys and gut during exercise

A

they vasoconstrict - mainly due to the effect of adrenaline and hormones which are orga specific. These organs have more alpha recepors

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12
Q

what happens to skeletal and cardiac muscle during exercise?

A

metabolic hyperaemia overcomes vasomotor drive - vasodilatation. have more beta receptors

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13
Q

what happens to blood flow to skeletal and cardiac muscle during exercise?

A

increases in proportion to metabolic activity

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14
Q

what does te increase in CO do to the BP?

A

increases systolic BP

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15
Q

what does the metabolic hyperaemia do to TPR and DBP?

A

decreases both (i.e. the pulse pressure increases) stong vasodilator effect of metabolites

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16
Q

what may happen post exercise?

A

may get a hypotensive response

17
Q

what is the effect of sympathetic stimulation on pacemaker cells?

A

Slope of Pacemaker Potential INCREASES
Pacemaker potential reaches threshold quicker
Frequency of action potentials increases - Positive chronotropic Effect

18
Q

what is the Effect of sympathetic nerve stimulation on ventricular contraction?

A

Peak ventricular pressure rises - contractility of heart at a given EDV rises

Frank-Starling Curve is shifted to the left

19
Q

what is the effect of EDV on SV?

A

increases SV

20
Q

what are examples of the chronic CV responses to regular exercise

A
  • Reduction in sympathetic tone and noradrenalile levels
  • Increased parasympathetic tone to the heart
  • Cardiac remodeling
  • Reduction in plasma renin levels - therefore reducing BP
  • Improved endothelial function: vasodilators vasoconstrictors
    Arterial stiffening