venous disease Flashcards

1
Q

describe venous insufficiency

A
  • Inadequate venous drainage of the lower extremities
  • CAUSE

–> clot

–> inheriteda bnormality of the veins

–> increased pressure in the venous system

  • Superficial = varicose veins
  • deep = chronic venous insufficiency
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2
Q

define thrombophlebitis

A
  • broad term
  • inflammation of vein with or without presence of a clot
  • most commonly involves great saphenous vein
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3
Q

describe risk factors of superficial thrombophlebitis

A
  • coagulation abnormalties
  • endothelial dysfunction
  • venous therapy (following vein ablation)
  • malignancy and hypercoagulable states
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4
Q

describe clinical features of thrombophlebitis

A
  • tenderness, induration, pain and erythema along the course of superficial vein
  • palpable cord
  • HIGH INDEX OF SUSPICION FOR DVT in patients with risk factors (prior DVT)

**feels like a piece of rope under skin**

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5
Q

describe tx of superficial thrombophlebitis

A
  • aimed at alleviating symptoms of pain, swelling

–> NSAIDs, Warm compress, elevation

  • thrombus prevention in the deep veins
  • anticoagulation in patients with extensive involvement or high risk patients
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6
Q

define varicose veins

A
  • dilated, elongated, tortuous
  • involves superficial veins 3mm or greater in size
  • affect 10-30% of population
  • seen more in older patients
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7
Q

describe pathophysiology of varicose veins

A
  • inadequate muscle pump
  • incompetent valves leading to reflux
  • venous obsturciton

**above components lead to increase venous pressure known also as venous hypertension

–> venous hypertension –> vein dilation –> skin changes –> skin ulceration

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8
Q

describe diagnosis/management of varicose veins

A
  • diagnosis

–> correlates with degree of venous reflux

  • identified by venous duplex ultrasound as retrograde flow of greater than .5 secs oin duration
  • management

–> conservative = elevation, compression, exercise

–> ablation therapy

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9
Q

describe chronic venous insufficiency

A
  • associated with structural and histologic changes

–> cappilary microcirculatory disorder

–> fibrin deposition

–> inflammation

**all of hte above impaire oxygenation of the skin and subcutaneous tissues

–> results in edema, hyperpigmentation, fibrosis and ulcer formation

TX: improve symptoms, reduce edema, healing and prevention of ulcers

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10
Q

describe general treatment of chronic venous insufficiency

A
  • Leg elevation

–> level of heart or above 30 minutes 3-4 times/days

–> helps to impove microcircualtion and reduce edema

  • exercise

–> walking or ankle flexion exercise to help with muscle pump

  • compression therapy = choice of compression varies from patient to patient
  • Skin care = emollients to lubricate dry skin
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11
Q

describe ulcer care

A
  • Debridement = removes devitalized tissue
  • Topical agents = enzymatic agents or silver sulfadiazine
  • Growth factors = oasis, epiflex
  • dressing options = hydrocolloids, absorbent dressings, occlusive dressings
  • Skin grafting/skin substitues = dermagraft, apligraf, STSG
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12
Q

describe the divisions of DVT

A
  • Distal = thrombus remains in the deep calf veins
  • Proximal = invovles popliteal, femoral or iliac veins (at or above knee)

–> the more proximal, the more common of a pulmonary embolus

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13
Q

describe the risk factors of DVT

A
  • Prolonged immobilization or bed rest
  • recent surgery
  • obesity
  • prior thromboembolism
  • lower extremity trauma
  • malignancy
  • oral contraceptives or hormone replacement therapy
  • pregnancy or postpartum
  • stoke
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14
Q

Describe the clinical presentation of DVT

A
  • Palpable cord
  • calf pain
  • unilateral leg edema with increase in calf diameter
  • warmth
  • tenderness
  • erythema
  • hohman sign = pain in the calf during dorsiflexion
  • wells score criteria
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15
Q

describe wells score criteria

A
  • Risk factors involved
  • used along with clinical exam
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16
Q

describe the diagnosis of DVT

A
  • Compression ultrasonography (venous duplex)

–> non-invasive modality of choice

–> positive predictive value of 94%

  • D-Dimer

–> negative D-Dimer as stand alone test may not be valid

–> often used in conjunction with wells score (pre-test probability)

  • patient wiht low probability wells score and negative D-dimer is UNLIKELY to have DVT are said to NOT need furhter testing
  • patient with moderate or high probability Wells score should be sent for ultrasound
17
Q

TX of DVT

A
  • Anticoagulation therapy - indicated in patient with symptomatic proximal DVT

–> PE is likely to occur in up to 50% of untreated patients

–> initial tx with anticoagulation should be started acutely

–> inferior vena cava filter (in case where anticoagulation is contraindicated or complicated or patient is high risk for PE