Venlafaxine Flashcards
What is another name for Venlafaxine
Effexor
The compound make of Venlafaxine
Big SERT
Small net -
“Dual action
How does venlafaxine work
It is suppose to increase both Serotonin and NE via transport inhibition.
What is another role of NET inhibition
increase dopamine in the PFC
Two major side effects of Venlafaxine
High blood pressure
Sweating
Why is Venlafaxine often given as an XR
You can take one day
Decreases GI side effects
How should we d/c Venlafaxine
We need to titrate down slowly, since it has such a short half life
Indicators for Venlafaxine
MDD
GAD
SAD
Panic
When should we expect a response
2 - 4 weeks
When should we consider dose changes
6- 8 weeks of nothing
California Rocker Fuel
Mirtazapine added. Usually for lack of response
Tests?
Blood pressure initially and throughout
Side effects of Venlafaxine
HTN
Nausea, Diarrhea or lack of appetite
Sweating
Sexual dysfunction
Low sodium
SIADH
Therapeutic dosage of Venlafaxine for GAD
150 - 225 mg
Therapeutic dosage of Venlafaxine for MDD
75 mg - 225 mg
