Vasopressors Flashcards
Dobutamine dose
10 mcg/kg/min
Dopamine dose
1 mcg/kg/min
Epinephrine dose
1-4 mcg/kg/min
Midodrine
10mg PO TID
Milrinone
0.5 mcg/kg/min
Norepinephrine
10-40 mcg/kg/min
Phenylephrine
150 mcg/kg/min
Vasopressin
0.04 U/min
Mechanism Dobutamine
B1 agonist
Mechanism Dopamine
Low dose is renal and mesenteric vasodilation.
High dose is inotropic and vasoconstrictive.
Mechanism Epinephrine
Alpha and Beta agonist
Mechanism Midodrine
Alpha agonist in both veins and arteries. Does not act on heart.
Mechanism Milrinone
PDE inhibitor with +inotropy and arterial vasodilation
Mechanism Norepinephrine
Alpha and Beta1 agonist
Mechanism Phenylephrine
Alpha agonist
Mechanism Vasopressin
ADH analog. Increases volume at kidneys.
When would you use Dobutamine?
Refractory CHF or when you need inotropy without vasodilation.
When would you use Dopamine?
Low dose for renal and mesenteric perfusion.
High dose for cardiogenic shock.
When would you use Epinephrine?
Asthma, Anaphylaxis, Cardiac Arrest.
When would you use Midodrine?
Orthostatic hypotension
When would you use Milrinone?
CHF
When would you use Norepinephrine?
Backbone pressor
When would you use Phenylephrine?
Treating moderate hypotension or as initial bolus on RACE.
When would you use Vasopressin?
As a third line in refractory shock.
