Vasculitis Treatment Flashcards

1
Q

henoch-schonlein purpura
first line

A

self-limiting

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2
Q

henoch-schonlein purpura
resistant disease

A

steroids + immunosuppression

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3
Q

polyarteritis nodosa
organ threatening

A

steroids + cyclophosphamide

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4
Q

polyarteritis nodosa
non-organ threatening

A

steroids + methotrexate/azathioprine

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5
Q

ANCA vasculitis
organ threatening
induce remission

A

steroids + cyclophosphamide

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6
Q

ANCA vasculitis
organ threatening
maintainence therapy

A

azathioprine

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7
Q

ANCA vasculitis
organ threatening
resistant disease
GPA/MPA only

A

rituximab + cyclophosphamide + IV Ig

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8
Q

ANCA vasculitis
non-organ threatening
induce remission
all subtypes

A

steroids

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9
Q

ANCA vasculitis
non-organ threatening
induce remission
GPA/MPA only

A

cyclophosphamide

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10
Q

ANCA vasculitis
non-organ threatening
maintenance therapy
GPA/MPA only

A

azathioprine + leflunomide

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11
Q

ANCA vasculitis
non-organ threatening
recurrent/resistant disease
EGPA only

A

mepolizumab

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12
Q

mepolizumab mechanism of action

A

IL-5 inhibitor

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