Vasculitis Treatment Flashcards
henoch-schonlein purpura
first line
self-limiting
henoch-schonlein purpura
resistant disease
steroids + immunosuppression
polyarteritis nodosa
organ threatening
steroids + cyclophosphamide
polyarteritis nodosa
non-organ threatening
steroids + methotrexate/azathioprine
ANCA vasculitis
organ threatening
induce remission
steroids + cyclophosphamide
ANCA vasculitis
organ threatening
maintainence therapy
azathioprine
ANCA vasculitis
organ threatening
resistant disease
GPA/MPA only
rituximab + cyclophosphamide + IV Ig
ANCA vasculitis
non-organ threatening
induce remission
all subtypes
steroids
ANCA vasculitis
non-organ threatening
induce remission
GPA/MPA only
cyclophosphamide
ANCA vasculitis
non-organ threatening
maintenance therapy
GPA/MPA only
azathioprine + leflunomide
ANCA vasculitis
non-organ threatening
recurrent/resistant disease
EGPA only
mepolizumab
mepolizumab mechanism of action
IL-5 inhibitor