Vasculitis Flashcards
Vasculitis?
Immune mediated vascular damage
The two large cell vasculitis are
Giant cell vasculitis
Takayasu arthritis
Giant cell arthritis
Affects above 50 years
Affects carotid artery resulting in headache visual disturbance pain while chewing)
Increased ESR over 100
Giant cell biopsy shows
Giant cell in elastic laminate
It’s segmental in which it needs to be taken along the section
Giant cell arthritis mgt is
Corticosteroids
Giant cell arthritis complications
Blindness
Takayasu arthritis
Less than 40 years of age
Mgt corticosteroids
Mostly affects aortic branch
Medium sized vasculitis
Kawasaki disease
Polyarthritis nedosa
Burgers disease
Kawasaki disease
Affects coronary artery
Poly arthritis nedosa
Trans mural inflammation
String of bead on angiogram is seen
Burgers disease causes clots in
Fingers and toes
20-40 years old age
Burgers disease biggest risk factor
Tobacco
Wegners granilomatosis
Small cell vasculitis
CANCA positive
Ssx
Saddle nose
Sinusitis
Oral ulcer
Kidney and lung disease
Wegners granilomatosis management
Corticosteroids and cyclophosphamide
Difference between Wegners granilomatosis and microscopic polyangitis is?
Microscopic polyangitis does not affect arteries in nose
PANCA is positive on WG
In MPA CANCA positive
