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Vasculits > Vasculitis > Flashcards

Vasculitis Flashcards

1
Q

medium sized artery vasculitis not assc with granulomas or glomerulonephristis

A

Polyarteritis Nodosa

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2
Q

Polyarteritis Nodosa necrotizing or non-necrotixing

A

necrotizing

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3
Q

VASO-OCCULSIVE Dz = Thrombosis

Predominantly affects the vascular supply to the lower limbs and HANDS!!!

A

Burgers

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4
Q

Associated with HepC viral infection

A
  1. Cryoglobulinemia Vasculitis

2. Cutaneous Polyarteritis Nodosum (limited to skin)

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5
Q

assc with Hep B

A

Polyarteritis Nodosa

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6
Q

assc with elevated IgA

A

Henoch-Schonlein Purpura

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7
Q

assc with eosinophillia

A

ergic Granulomatosis With Polyangiitis [AGPA] (Churg Strauss Syndrome)

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8
Q

Antibodies directed against collagen, elastin, lamin, endothelial cells

ANCAs directed against MPO, lactoferrin and elastin

A

Bergurs

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9
Q

Immune complex (IC)-mediated small vessel vasculitis of the skin

In capillaries, post cap venules, and arterioles

A

Hypersensitivity Vasculitis

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10
Q

Classic tetrad of purpura, arthritis, abdominal pain, GN

A

Henoch-Schonlein Purpura

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11
Q

AM stiffness, shoulder + pelvic girdle pain

A

Polymyalgua rheumatic (in association with GCA)

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12
Q

adolescent girls and young women of Asian descent < 40 yo

A

Takayasu’s Arteritis

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13
Q

glomerulonephritis and lung involvement with pulmonary hemorrhage

A

Microscopic Polyangiitis

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14
Q

Classic Triad of ENT, respiratory tract and kidney involvement

A

Granulumatosis With Polyangiitis (Wegener’s Granulomatosis)

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15
Q

livedo reticularis

A

Polyarteritis Nodosa

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16
Q

Necrotizing vasculitis of small vessels, primarily postcapillary venules

NOT associated with granulomas

A

Henoch-Schonlein Purpura

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17
Q

pANCA

A

Microscopic Polyangiitis

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18
Q

Associated with glomerulonephritis and granuloma formation with a palaside of histiocytes (~rheumatoid nodules)

A

Granulumatosis With Polyangiitis (Wegener’s Granulomatosis)

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19
Q

TRIAD OF: asthma + eosinophilia + vasculitis

A

Allergic Granulomatosis With Polyangiitis [AGPA] (Churg Strauss Syndrome)

20
Q

ocular lesions
pyoderma gangenousum
arthritis
Oral and genital ulcers

A

Bechet’s Disease

21
Q

Vasculitis confined only to the brain, meninges, or spinal cord.

A

Primary Angiitis of the CNS

22
Q

Neutrophils + fibrinoid necrosis

A

Polyarteritis Nodosa

23
Q

leukcoyotoclasia (destruction of WBCs)→ dispersing nuclear dust

A

Hypersensitivity Vasculitis

24
Q

iAssociated with purpura, arthritis, glomerulonephritis, and colicky abdominal pain

A

Hypersensitivity Vasculitis

25
Q

non-blanching purpura classically of lower extremities/buttocks

A

Henoch-Schonlein Purpura

26
Q

antibodies that ppt from serum in cold , resolubilize upon warming

A

Cryoglobulins

27
Q

fever, weight loss, fatigue
Palpable purpura with ulcers
Digital ischemia

A

Cryoglobulinemia Vasculitis

28
Q

Giant cells eat up internal elastic lamina

A

GCA

29
Q

Granulomatous inflammation of AORTA and its branches

Medial loss of elastic fibers → thinning → Aneurysm or dissection

A

Takayasu’s Arteritis

30
Q

strawberry tongue

A

Kawasaki Disease

31
Q

hypocomplementemia and ↑↑ANAs

A

Connective Tissue Disease Associated Vasculitis

32
Q

Pupuric lesions

Deep cutaneous ulcer over malleoli

A

Rheumatoid Vasculitis

33
Q

eosinophilic granulomas of the urinary tract and/or prostate

A

Allergic Granulomatosis With Polyangiitis [AGPA] (Churg Strauss Syndrome)

34
Q

Most commin in 20’s and 30’s

with oral or genital ulcers

A

Bechet’s Disease

35
Q

Adults: Usually following drug exposures (sulfas, penicillins, diuretics, allopurinol, phenytoin)

Kids: UTR infections

A

Hypersensitivity Vasculitis

36
Q

↓C4

A

Cryoglobulinemia Vasculitis

37
Q

leukocytoclastic vasculitis with IgM + C3 deposits in/around small and medium sized vessels

A

Cryoglobulinemia Vasculitis

38
Q

Pathogenesis: Ag recognition in adventitia → IFN-γ →macrophages form giant cells→ arterial wall destruction + occlusive intimal hyperplasia

A

GCA

39
Q

erythema of palms/soles

A

Kawasaki Disease

40
Q

Jaw or tongue claudication

A

GCA

41
Q

Type of Igs in Cryoglobulinemia Vasculitis

A

IgG and M

42
Q

Necrotizing vasculitis affecting small vessels, but no granulomas

A

Microscopic Polyangiitis

43
Q

can progress to sudden blindness

A

GCA

44
Q

Testicular tenderness

A

Polyarteritis Nodosa

45
Q

Infectious causes og vasculitis
Fungal =?
Bacterial =?
viral =?

A 
Fungal = aspergillus
Bacterial = pseudomonas
viral = CMV

Vasculits (1 decks)

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