Vasculitis

Question 1

Giant cell (temporal) arteritis

Answer 1

Temporal artery
Headache, ocular symptoms,fascial pain
T cell mediated immune response
Granulomatous inflammation
\+50year

Question 2

Takayasu arteritis(autoimmune)

Answer 2

Aortic arch,arch vessels
Pulmonary, renal, coronary arteries
Granulomatous inflammation
Pulmonary, renal hypertension
Leg ischemia,MI
-50year

Question 3

Polyarteritis nodosa(immune complex mediated)

Answer 3

Renal,vesceral arteries

Fever of unknown cause, abdominal pain, hypertension,bloody stool, anuerysm that rupture causing hemorrhage

Question 4

Kawasaki disease (anti endothelial cell mediated)

Answer 4

Infants,skin and cutenous manifestation,eye very red,fever,rash
Strawberry tongue

Question 5

Wegner granulomatosis(granulomatosis with poly angitis)ANCA

Answer 5

Granulomas in lung
Vasculitis of lung
Glomerulonephritis

Question 6

Churg struauss syndrome(ANCA)

Answer 6

Granuloma of lung
Asthma
Esinophilia

Question 7

Microscopic polyangitis(ANCAs)

Answer 7

Vasculitis
No granulomatous
Hemoptysis, hematuria

Question 8

Thromboangiitis obliterans (burger’s disease)

Answer 8

Acute, chronic inflammation+thrombosis
Organization+recanalization
Heavy tobacco smockers
Cold sensitivity of the hand,pain in foot,trophic skin ulcer
Gangrene of the limb

Question 9

Raynaud’s phenomenon

Answer 9

Intermittent vc dt cold
Pallor , cyanosis
Red, white and blue

Question 10

Benign tumor of blood vessels

Answer 10

Capillary, cavernous hemangioma
Glomus tumor(glomangioma)

Question 11

Glomus tumor

Answer 11

Benign, painful tumor arising from glomus body

Under fingernails

Question 12

Malignant tumors

Answer 12

Angiosarcoma

Kaposi sarcoma