Vascular System Flashcards

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1
Q

Aorta

A

Blood is pumped into

branches into a series of arteries

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2
Q

Route of blood

A

Deoxygenated blood is pumped into the AORTA-> branches into arteries which then branch into arterioes which then branch into capillaries–> blood is oxygenated –> capillaries converge into venules –> converge into veins –> blood deoxygenated–> blood back to the heart

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3
Q

Right side of heart

A

pumps deoxygenated blood into pulmonary circulation

Right ventricle not as muscular

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4
Q

ventricle

A

lower chambers of heart, right and left

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5
Q

Left side of heart

A

pumps oxygenated blood into systemic circulation (throughout the body)
Left ventricle more muscular than right because it has to pump blood to all the body, has to pump against a higher resistance

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6
Q

atrioventricular valves

A

located between the atria and ventricles on both sides of the heart prevent backflow of blood into the atria

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7
Q

tricuspid valve

A

valve on right side of the heart

has three cusps

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8
Q

mitral valve

A

valve on left side of the heart

has two cusps

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9
Q

semilunar valve

A

have three cusps
located between the left ventricle and the aorta (aortic valve) and between the right ventricle and the pulmonary artery (pulmonic valve)

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10
Q

systole

A

period of heartbeat during which the ventricles contract

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11
Q

diastole

A

period of heartbeat when cardiac muscles relax and blood drains into all four chambers of the heart

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12
Q

cardiac output

A

total volume of blood the left ventricle pumps out per minute. heart rate x stroke volume

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13
Q

Sinoatrial Node

A

(SA NODE) pacemaker, small mass of specialized tissue located in the wall of the right atrium, spreads impulses through both atria stimulating them to contract simultaneously. Ordinary cardiac contraction originates in and is regulated by the SA node

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14
Q

Atrioventricular Node

A

AV node, impulse from SA node arrives here, conducts slowly, allows time for atrial contraction and for the ventricles to fill with blood

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15
Q

Bundle of His (AV bundle)

A

carries impulse from SA–>AV–> bundle of His, which branches into the right and left bundle branches

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16
Q

purkinje fibers

A

impulse goes through here after SA->AV–> AV bundle, in the walls of both ventricles which causes a strong contraction

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17
Q

Autonomic Nervous System

A

modifies the rate of heart contraction

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18
Q

vagus nerve

A

Parasympathetic system innervates the heart by using this, causes a decrease in heart rate.

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19
Q

Sympathetic System Action

A

innervates the heart via the cervical and upper thoraic ganglia and causes an increase in heart rate. Adrenal medulla exerts hormonal control via epinephrine secretion which causes an increase in heart rate

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20
Q

Three types of blood vessels

A

arteries, veins, and capillaries

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21
Q

Arteries

A

thick walled, muscular, elastic vessels, transport oxygenated blood away from the heart except for the pulmonary arteries which transport deoxygenated blood from the heart to the lungs.

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22
Q

veins

A

relatively thin arteries, inelastic vessels that conduct deoxygenated blood to the heart (EXCEPT FOR PULMONARY VEINS)

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23
Q

pulmonary veins

A

carry oxygenated blood from the lungs to the heart

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24
Q

stroke volume

A

volume of blood pumped out of the left ventricle per contraction

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25
Q

Lymphatic System

A

secondary circulatory system, vessels transport interstitial fluid called lymph to the cardiovascular system keeping fluid levels in the body constant.

26
Q

Lacteals

A

The smallest lymphatic vessels, collect fats in the form of chlomicrons from the villi in the small intestine and deliver them into the bloodstream bypassing the liver

27
Q

Lymph Nodes

A

swellings along lymph vessels containing phagocytic cells called lymphocytes that filter the lymph, removing and destroying foreign particles and pathogens

28
Q

Blood

A

four to six liters in the body, both liquid (55%) and cellular components (45%)

29
Q

Plasma

A

Liquid component of blood, aqueous mixture of nutrients, salts, respiratory gases, wastes, hormones, and blood proteins

30
Q

Cellular Components of Blood

A

Erythrocytes, leukocytes, and platelets

31
Q

Erythrocytes

A

red blood cells: oxygen carrying components of blood, contains approximately 250 million molecules of hemoglobin, distinct biconcave shape for increased surface area and flexibility, formed from stem cells in the capillaries that lose their nuclei, mitochondria, and membranous organelles

32
Q

Leukocytes

A

White blood cells: Main component of the immune system. larger than erythrocytes, protective functions. Phagocytize foreign matter, migrate from blood to tissue where they mature into a macrophage. Lymphocytes are involved in immune response and the production of antibodies (B Cells) or cytolysis of infected cells (T cells)

33
Q

oxyhemoglobin

A

hemoglobin bound to four oxygen

34
Q

platelets

A

cell fragments that lack nuclei and are involved in clot formation, involved in injury repair

35
Q

deoxyhemoglobin

A

hemoglobin bound to carbon dioxide

36
Q

Transport of Nutrients

A

amino acids and sugars are absorbed into the blood stream at the intestinal capillaries and after processing are transported throughout the body.

37
Q

Transport of waste

A

diffuse into capillaries from surrounding cells, then delivered to the appropriate excretory organs

38
Q

Platelet Plug

A

forms when platelets come in contact with exposed collagen of a damaged vessel which then release a chemical that causes platelets to adhere to one another

39
Q

Thromboplastin

A

Clotting factor released by platelets and the damaged tissue. Cofactors are calcium and vitamin K. It coverts the inactive plasma protein prothrombin to the active form thrombin.

40
Q

Thrombin

A

Active form of Prothrombin. Converts fibrinogen, a plasma protein, into fibrin.

41
Q

Fibrin

A

Threads of fibrin coat the damaged area and trap blood cells to form a clot.

42
Q

Serum

A

fluid left after blood clotting

43
Q

Process of Clotting

A

Platelets in contact with exposed collagen–> thromboplastin released-> (prothrombin to thrombin)–> (fibrinogen to fibrin)-> traps blood cells to clot

44
Q

humoral immunity

A

compromised by specific immunity, involves the production of antibodies

45
Q

cell-mediated immunity

A

cells combat fungal and viral infections

46
Q

skin

A

Nonspecific defense mechanisms, barrier against bacterial invasion

47
Q

mucus- coated epithelia

A

Nonspecific defense mechanisms, filter and trap foreign particles

48
Q

macrophages

A

Nonspecific defense mechanisms, engulf and destroy foreign particles

49
Q

Inflammatory response

A

Nonspecific defense mechanisms, injured cells release histamine which causes blood vessels to dilate increasing blood flow to the region. Granulocytes are attracted to the injured site and phagocytize antigenic material. Also accompanied by fever, interferons produced and diffuse to other cells to prevent spread of virus

50
Q

Allergic reaction

A

inappropriate response to certain foods and pollen cause the body to form antibodies and release histamine

51
Q

Immunoglobulins (aka Antibodies)

A

Humoral Immunity, complex proteins that recognize and bind to specific antigens and trigger the immune system to remove them.

52
Q

Leukocytes (Humoral Immunity Response)

A

attracted by antibodies, phagocytize the antigen or cause the antigen to clump together, agglutinate, and form large insoluble complexes, facilitating their removal by phagocytic cells.

53
Q

Active Immunity

A

refers to production of antibodies during an immune response, can be conferred by vaccination, stimulates the immune system to produce specific antibodies against it

54
Q

Passive Immunity

A

transfer of antibodies produced by another individual or organism, acquired passively or by injection. lasts only as long as the antibodies circulate in the blood system.

55
Q

Gamma globulin

A

fraction of the blood containing a wide variety of antibodies, can be used to confer temporary protection against hepatitis and other diseases by passive immunity

56
Q

antigens

A

Characteristic cell surface proteins on erythrocytes. Macromolecules that are foreign to the host organism and trigger an immune response. Two major groups of red blood cell antigens: ABO group and Rh factor.

57
Q

Blood type A

A

antigen: A
Antibody: anti-B
Can donate to: A and AB
Can receive from: A and O

58
Q

Blood type B

A

antigen: B
Antibody: anti-A
Can donate to: B and AB
Can receive from: B and O

59
Q

Blood type AB

A

antigen: A and B
Antibody: none
Can donate to: AB only
Can receive from: universal acceptor

60
Q

Blood type O

A

antigen: none
Antibody: anti-A and anti-B
Can donate to: all Universal Donor
Can receive from: O only

61
Q

Rh Factor

A

may be present on the surface of a red blood cell. Rh+ or Rh-. Especially important during pregnancy.