Vascular Surgery Flashcards
Describe the clinical presentation of acute limb ischaemia
The 6Ps
Pain Pallor Paraesthesia Pulselessness Paralysis Poikilothermia (cold limb)
What is the etiology of acute limb ischaemia?
Cardiac embolism
Thrombosis
Trauma
What are the classic angiographic finding of an embolism
Sudden cutoff
Convex filling defect
Otherwise relatively normal vessels
No visible atherosclerosis
Often lodge at bifurcations
List some of the causes of a cardiac embolism
Atrial fibrillation
MI with mural thrombosis
Ventricular aneurysm
Mechanical valve
Endocarditis
Atrial myxoma
List some of the causes of a thrombosis
Atherosclerosis obstruction
Previous bypass/stent
Peripheral aneurysms - popliteal
Hypercoaguable states
Aortic Dissection
Cocaine/vasopressors
What are the angiography findings of atherosclerosis
Diffuse atherosclerosis
Tapered irregularly cutoff vessels
Well developed collaterals
List some risk factors for a hypercoaguable state
Malignancy
HIV
Anti-phospholipid syndrome
Heparin induces thrombocytopenia
Inherited thrombophilia
Provide a DDx of acute limb ischaemia
Shock
Venous threatened limb
Acute compression neurology
Guillain Barre
Describe the Rutherford classification of acute ischemia for a 2b threatened limb
Salvageable if immediately treated
Slow/absent capillary refill
Partial muscle paralysis
Partial/complete sensory loss
Inaudible arterial Doppler signals
Audible venous Doppler signals
Describe the Rutherford classification of acute ischemia for a non-viable limb
Primary amputation needed
Absent capillary refill - fixed skin staining due to ruptured capillaries
Complete tense muscle paralysis - flexor rigidity (stiff ankle)
Complete sensory loss
Inaudible arterial Doppler signal
Inaudible venous Doppler signal
What special investigations would you do in a patient with suspected acute limb ischaemia?
CT angiography
Digital subtraction angiography (DSA)
Ultrasound - Doppler flow
MR angiography
What is the management of acute limb ischaemia?
Heparin 5000 IU - prevention of further thrombosis
Oxygen
IV analgesia
Embolectomy/thrombolectomy
Bypass surgery
Amputation
What are the complications of revascularization?
Reperfusion injury
Oxygen free radicals damage cell membrane
Compartment syndrome
Systemic release of lactate, potassium and myoglobin
What are the risk factors for chronic arterial disease (critical limb ischaemia)
Smoking
DM
HPT
Hyperlipidaemia
Older age
Obesity
Males and post menapausal women
Family history
Chronic renal failure
What are the symptoms of chronic arterial disease?
Usually asymptomatic
Intermittent Claudication - ischaemic muscle pain induced by exercise and relieved by rest
Critical limb ischaemia:
Rest pain - severe burning pain in the forefoot or toes that’s worse at night and improves with walking or hanging the limb off the bed
Gangrene
Ischaemic ulcer
Impotence - aortic-iliac/bilateral iliac disease
Acute on chronic vascular occlusion
Provide a DDx for claudication
Osteoarthritis of the hip/knee
Neurospinal claudication
Chronic compartment syndrome
Venous claudication
Provide a DDx for rest pain
Diabetic neuropathy
Gout
Plantar fasciitis
Night cramps
What is critical limb ischaemia (CLI)?
It implies impending limb loss
When the blood supply to a limb is critically diminished
Often a multilevel disease
What are the symptoms/signs of critical limb ischaemia?
Rest pain
Non-healing ischaemic ulcer
Gangrene
When assessing a patient the femoral pulse and all pulses below it are absent. What is anatomical level of disease?
Aorta-iliac disease
When assessing a patient the highest pulse palpable is the popliteal pulse. What is anatomical level of disease?
Trifurcation disease