Vascular Problems - Arterial/Venous Flashcards
Vascular system starts with the left heart that pumps oxygen-rich blood through arteries, arterioles, capillary system (where you have O2 and CO2 exchange with the cells of the body)
Venules and veins return the O2 poor, CO2 rich blood to the right side of the heart to the lungs
- With peripheral circulation, we’re dealing with 2 groups of very different diseases - venous and arterial - that will exhibit with different symptoms and be treated differently
Peripheral Arterial Disease (PAD)
- Affects ~12% of people in the US
- Men are affected more commonly than women before menopause; then, women surpass men
- 50-75% of clients with PAD have clinically significant coronary artery disease (CAD)
- CAD may be silent because PAD prevents clients from exerting themselves enough to trigger angina
Pathophysiology of PAD
- Insufficiency of the peripheral circulation
- Atherosclerotic plaques narrow the arterial lumen impeding oxygenated blood flow to distal tissues
- Stenosis (narrowing) and occlusion (blockage)
Risk Factors
- # 1 > smoking (includes passive smoking)
- Male gender
- HTN
- High LDL/low HDL cholesterol
- Diabetes
- Family h/o atherosclerosis
- Obesity/sedentary lifestyle
- High homocysteine and CRP levels
- Stress
Homocysteine and C-reactive proteins increase __ formation and increase the propensity for __ formation; risk factor for atherosclerosis
thrombin
thrombus
Signs & Symptoms - What are the 6 P’s?
- Pain
- Pallor
- Pulse
- Paresthesia
- Paralysis
- Poikilothermia
?
Is the inability to maintain a constant core temperature independent of ambient temperature
Poikilothermia
- 20% asymptomatic (b/c not active enough to induce symptoms)
- Intermittent claudication/progress to pain at rest
- Nocturnal pain/improved with dangling extremity
- Delayed capillary refill
- Waxy appearance of extremity
> Extremity pallor when elevated
> Extremity rubor when dependent
- Diminished or absent peripheral pulses
- Skin is thin, waxy, and with hair loss
- Skin is cool to touch
- Cyanosis (r/t decreased arterial flow to tissues) [extremity may even be diaphoretic r/t sympathetic overactivity]
- Ulcers
- Dry and wet gangrene [risk of cellulitis]
- Painful
- Progression to paresthesia and paralysis
- Painful unless there is peripheral neuropathy from diabetes or alcoholism
- Pulseless, cold, painful, paresthesia and paralysis may be indicative of acute embolic syndrome
- PAD ulcers usually small, round, necrotic with minimal or no drainage
Diagnostics - Noninvasive
- Doppler - segmented systolic BP measurements of the LE
- (ABI) Ankle/Brachial Index
- MRI
- Exercise Tolerance
Diagnostics - Invasive
- Arteriography
Doppler - segmented systolic BP’s of LE
- Normally BP’s in LE are higher than UE
- With PAD, UE BP’s are higher than LE
- Mild disease - diff of 10-30 mmHg
- Severe disease - diff of 40-50 mmHg
?
Is the ratio of systolic BP in the ankle to systolic BP in the arm
Derived by dividing the ankle systolic pressure with brachial systolic pressure
With increased stenosis, there’s a decrease in the systolic pressure distal to the stenosis/occlusion
ABI
- Claudication 0.90-0.50
- Rest pain 0.49 or less, severe ischemia and tissue loss 0.25 or less
- > 1.3 indicates calcification of vessels from DM, CRF, hyperparathyroidism
Exercise Test
- If there’s a drop in ankle pressure by 40-60 mmHg for 20-30 sec and a decrease in pulse volume waveform, this is indicative of PAD
- Screen for CAD for surgical procedures
Nursing Interventions
- Meticulous foot care
- Monitor and treat pain (no cold or warm packs r/t ischemia and increased trauma)
- Legs in the dependent position
- Monitor for the development of ulcers
- Wound care as ordered
- Antibiotics as ordered for cellulitis
- Encourage moderate amount graded ambulation once initial infection resolved and healing begins
- Encourage adequate PO fluids (fluids to decrease viscosity of blood)
- Surgical interventions: aorta-femoral bypass, embolectomy
- Avoid the cold
- Diet of protein, vitamin A, C, zinc
- Avoid leg crossing
- CMS checks
> Palpate dorsal pedis, posterior tibialis, popliteal and femoral pulses > doppler
- NPO and IV for angiogram or surgical intervention
- ___ (cilostazol), ___ (pentoxifylline), ___ (clopidogrel), aspirin
- Review of antihypertensives
Pletal, Trental, Plavix
Pletal (antiplatelet/vasodilator)
- HA, diarrhea, abnormal stools, palpitations, tachycardia
Trental (hematological agent)
- Xanthine
- May potentiate antihypertensives and anticoagulants (! know bleeding precautions)