Vascular Disease Flashcards
Treatment for atherosclerosis?
Stop smoking Exercise Nutrition Antiplatelet drugs Beta blockers, statins, antihypertensives
Is there infection with wet gangrene? Dry gangrene?
Wet: yes; with cellulitis and purulent drainage
Dry: no; mummification without infection
What diagnostics do we need with peripheral vascular disease?
ABI: >9 is normal; less then 0.8 is claudication; less than 0.4 is rest pain or tissue loss-DO THIS
Color flow doppler ultrasound-DO THIS
Magnetic resonance angiography-gold standard
What does an ABI >1 indicate?
Calcification
Treat for mild to moderate claudication without rest pain or tissue loss?
Non-operatively:
- Graded exercise (40-60 mins most days)
- Antiplatelets
Treatment for severe claudication with interference?
Stop smoking; control HTN, DM, cholesterol
Antiplateets
Operative management
What is an acute arterial occlusion?
- Sudden onset of pain
- Usually an acute thrombosis from a chronically stenosed vessel; can be thromboembolism (a-fib; AA)
- The 6 P’s
- Treatment: immediate thrombectomy if ischemia; anticoagulation; if no ischemia thrombolytic therapy
How long does leg ischemia take to cause a reperfusion injury?
Over 6 hours
What is a reperfusion injury?
- Leg ischemia over 6 hours
- Neutrophils migrate; limb swells; cell leakage leads to acidosis, hyperkalemia, ATN and free radical formation
Can you have carotid bruits without stenosis?
Yes, and you can have stenosis without a bruit
How do we diagnose/screen for carotid artery stenosis?
Carotid US
MRA?
Arteriography
Treatment for mild to moderate carotid artery stenosis?
Antiplatelet or anticoagulation: controversia
Routine surveillance
Tx of risk factors
Treatment for severe or symptomatic carotid stenosis?
Endarterectomy of carotid
When should we treat carotid artery stenosis?
Symptomatic patients with >50% stenosis
Asymptomatic, healthy patients with >60% stenosis
Contraindications to carotid artery endarterectomy?
Occluded artery
Severe neurologic deficit following CVA
Concurrent serious medical illnesses
Treatment for Buergher’s disease?
STOP SMOKING
Patients may have superficial thrombophlebitis of hands and feet
What can cause renal artery stenosis in young female patients?
Fibromuscular dysplasia
Treatment for renal artery stenosis?
Angioplasty w/ stenting
Endarterectomy
How doe we diagnose renal artery stenosis?
Renal US
Most common spots for aneurysms?
Infrarenal aorta
Iliac arteries
Popliteal arteries
What are false aneurysms associated with?
Injuries and infections
Which aneurysms tend to rupture?
AAA and iliac aneurysms
Popliteal and femoral rarely rupture; can cause thrombi that embolize arteries of the calf and foot
Best diagnostic for an asymptomatic aneurysm?
US
If elective surgery is planned on an aneurysm, what do we always need?
CTA or arteriogram
At what size do AAAs become pulsatile?
Over 5 cm
Classic triad of symptoms for ruptured AAA?
Sudden back pain
Hypotension
Pulsatile abdominal mass
When should we operate on an AAA?
-Asymptomatic: Over 5-5.5 cm in men
Over 4.5 cm in women
-Rapidly enlarging
-Symptomatic