VAP and HAP Flashcards

1
Q

Q: What is pneumonia and what are its common causative agents?

A

A: Pneumonia is a lung infection causing inflammation in one or both lungs. It is most often caused by bacteria like Streptococcus pneumoniae or viruses such as influenza, and rarely by fungi.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Q: What are the main types of pneumonia based on the setting in which they develop?

A

A: The main types are community-acquired pneumonia (CAP), hospital-acquired pneumonia (HAP), and ventilator-acquired pneumonia (VAP).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Q: What is community-acquired pneumonia (CAP)?

A

A: CAP develops outside of a hospital or within 48 hours of hospital admission.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Q: What is ventilator-acquired pneumonia (VAP)?

A

A: VAP refers to pneumonia that occurs in patients on mechanical ventilation, 48 hours after endotracheal intubation.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Q: What are the initial steps when a patient presents with signs of HAP or VAP?

A

A: Obtain a focused history and physical exam, order labs (CBC, procalcitonin), use pulse oximetry, collect blood cultures, and obtain chest imaging.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Q: What are common symptoms and signs of HAP?

A

A: Symptoms include fever, productive cough, pleuritic chest pain, and shortness of breath. Signs include elevated temperature, tachypnea, tachycardia, rales, and decreased breath sounds.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Q: What lab findings are typically seen in HAP?

A

A: Elevated WBC count and procalcitonin levels, and reduced oxygen saturation on pulse oximetry.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Q: What does chest imaging usually reveal in HAP?

A

A: New lung infiltrate, consolidation, or effusion.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Q: What is the acute management for HAP?

A

A: Continuous monitoring of heart rate, blood pressure, oxygen saturation, and providing supplemental oxygen if needed. Collect sputum samples for gram stain and cultures.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Q: How is sputum collected in HAP?

A

A: By sputum induction, where the patient inhales a saline mist to trigger a cough, releasing sputum for lab analysis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Q: What are the key diagnostic steps for VAP?

A

A: Discuss with hospital staff, review the medical chart, perform a physical exam, order labs (CBC, procalcitonin), and obtain point-of-care lung ultrasound imaging.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Q: What imaging is preferred for diagnosing VAP?

A

A: Point-of-care lung ultrasound, which is ideal for patients who cannot be easily transported.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Q: What does acute management for VAP involve?

A

A: Continuous monitoring of heart rate, blood pressure, oxygen saturation, and ventilatory parameters, and adjusting ventilator settings as needed.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Q: How is sputum collected in VAP?

A

A: Through bronchoalveolar lavage (BAL) or mini-BAL, as patients are intubated and unable to perform sputum induction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Q: What are the risk factors for multidrug-resistant (MDR) pathogens in pneumonia?

A

A: IV antibiotic use in the last 90 days, a hospital stay of 5 or more days, acute renal replacement therapy, ARDS prior to VAP, or septic shock at the time of VAP.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Q: What empiric antibiotic therapy is used for patients with risk factors for MDR pathogens?

A

A: A combination of an antipseudomonal beta-lactam and a non-beta-lactam, plus MRSA coverage if necessary.

17
Q

Q: What is the treatment for patients without MDR risk factors?

A

A: IV antibiotic monotherapy with piperacillin-tazobactam, cefepime, a respiratory fluoroquinolone like levofloxacin, or a carbapenem.

18
Q

Q: How should you follow up on microbiological testing results?

A

A: Tailor antibiotics based on test results, assess patient response after 48 hours, and adjust treatment as needed based on clinical status and biomarkers like procalcitonin levels.

19
Q

Q: What should be done if microbiological testing results are negative?

A

A: Assess patient response to empiric antibiotics after 48 hours, continue antibiotics if improving, or consider pneumonia-related complications or alternative diagnoses if not improving.