VALVULAR HEART DISEASES Flashcards
valve lesions that are: pressure overload vs. volume overload
pressure overload = mitral stenosis, aortic stenosis
volume overload = mitral regurgitation, aortic regurgitation
preoperative evaluation goals of patients w/ valvular heart disease
- ascertain the severity of the disease
- the degree of impaired contractility
- presence of associated major organ system disease
- recognition of compensatory mechanisms
- evaluation of drug therapy
New York Heart Association Functional Classification of Patients with Heart Disease
Class I = asymptomatic
Class II = symptoms w/ ordinary activity but comfortable at rest
Class III = symptoms w/ minimal activity but comfortable at rest
Class IV = symptoms at rest
systolic murmur
could reflect:
- stenosis of aortic or pulmonic valves
- incompetence of mitral or tricuspid valves
diastolic murmur
could reflect:
- stenosis of mitral or tricuspid valves
- incompetence of aortic or pulmonic valves
angina in pt w/ valvular dz
not necessarily representative of CAD, but the two dz often co-exist
- increased myocardial O2 demand 2/2 ventricular hypertrophy
complications associated w/ prosthetic heart valves
- valve thrombosis
- systemic embolization
- structural failures
- hemolysis
- paravalvular leak
- endocarditis
management of anticoagulation pre-operatively in pts w/ prosthetic valves
- continue anticoagulation in minor surgery
- bridge w/ heparin (d/c warfarin 3-5 days preop) for major surgery
SBE guidelines
Conditions
- prosthetic valve
- previous endocarditis
- congenital heart disease: unrepaired, repaired w/ prosthesis w/in 6 months, or prosthetic repair w/ residual defects
- cardiac transplantation w/ development of valve problems
Procedures
- dental w/ perforation of oral mucosa
- invasive of respiratory tract
- invasive of infected skin/musculoskeletal
mitral stenosis: cause
rheumatic fever (by FAR most common)
mitral stenosis: symptoms
as a result of high LAP
- DOE
- orthopnea
- paroxysmal nocturnal dyspnea
SV not impaired at rest 2/2 compensatory increased LAP, but SV decreases w/ tachycardia or afib
mitral stenosis: valve gradient
mild = 6mmHg moderate = 6-10mmHg severe = >10mmHg
mitral stenosis: symptomatic at what size & transvalvular pressure?
normal mitral valve orifice = 4-6cm^2
- symptomatic at <50%
at valve area <1cm^2:
- mean LAP of 25mmHg is required to maintain CO
- chronic pulm HTN is likely if mean LAP >25mmHg
- -> predispose to pulm edema
mitral stenosis: what are these pts more at risk for?
- pulmonary edema
- decreased CO w/ exertion or hyperdynamic states
- thromboembolic events
- afib 2/2 LA enlargement
mitral stenosis: tx
- control HR to allow for LV filling (prevent increases in LAP)
- anticoagulation w/ concurrent afib
- diuretics if pulm edema
mitral stenosis: anesthetic management
prevent events that can decrease CO or produce pulmonary edema
- avoid tachycardia
- cardiovert or at least rate control if pt develops afib
- avoid excessive periop fluid admin, trendelenburg (precipitate CHF)
- avoid sudden SVR decrease (compensatory tachycardia not tolerated); give sympathomimetic like phenylephrine
- maintain contractility (used balanced technique, not just volatiles)
- avoid light anesthesia
mitral regurgitation: cause
- rheumatic fever (usually associated w/ mitral stenosis
- ischemic heart disease
- papillary muscle dysfunction
mitral regurgitation: pathophysiology
portion of every SV goes back into the LA
- -> LA volume overload & pulmonary congestion
- -> decreased SV = decreased CO
mitral regurgitation: severity dependent on?
- size of mitral valve orifice
- heart rate (determines duration of ventricular ejection)
- pressure gradients across the mitral valve
mitral regurgitation: severity as indicated by area of MR jet
mild = <3cm^2 --> 20-30% regurgitation moderate = 3-6cm^2 --> 30-50% regurgitation severe = >6cm^2 --> >55% regurgitation
what will you see on the PAOP waveform w/ mitral regurgitation?
V WAVE
- size of V wave correlates w/ magnitude of the mitral regurgitation
mitral regurgitation: management of anesthesia
improve forward LVSV; decrease regurgitant fraction
- prevent bradycardia
- prevent SVR increases (tx w/ nitro)
- minimize myocardial depression (tx w/ inotrope)
- monitor V wave
- use iso/des/sevo = decrease SVR, comp HR increase, minimal cardiac depression
- can use opioid if LVF, avoid bradycardia
mitral regurgitation: induction
pancuronium +/-? increases HR
- prevent increase in SVR & HR decrease
mitral valve prolapse: pathophysiology
prolapse of one or both mitral leaflets into the LA during systole +/- mitral regurgitation
mitral valve prolapse: anesthetic management
tx like regurg if they have it + take measures to minimize regurg
- larger ventricle = less prolapse & regurg than smaller ventricle
- thus take measures to keep LV full
- -avoid SNS activity
- -avoid decreased SVR
- -avoid rapid position changes to upright
- avoid hypovolemia
aortic stenosis: development & risk factors
degeneration & calcification of the aortic leaflets, and subsequent stenosis (aging) - those w/ bicuspid aortic valve develop AS earlier
risks
- systemic HTN
- hypercholesterolemia
aortic stenosis: valve area + pressure gradients
normal area = 2.5-3.5cm^2
mild = 1.0-1.5cm^2 + <20mmHg moderate = 0.8-1.0cm^2 + 20-50mmHg severe = <0.8cm^2 + >50mmHg
aortic stenosis: symptoms & pathophysiology
obstruction to ejection of blood into the aorta
- angina 2/2 increased myocardial O2 requirements (hypertrophy) + decreased delivery
- syncope 2/2 uncompensated exercise induced decrease in SVR
CLASSIC TRIAD:
- angina
- syncope
- DOA
aortic stenosis: anesthetic management
- maintain NSR
- avoid HR changes (bradycardia or tachycardia)
- avoid hypotension
- maintain preload
basically, avoid hypotension or any change that will decrease CO
aortic regurgitation: pathophysiology
decreased CO 2/2 regurgitation of part of the ejective SV back into the LV = pressure + volume overload
magnitude depends on
- HR (time available for regurgitation to occur)
- pressure gradient across the aortic valve (determined by SVR)
aortic regurgitation: anesthesia management
goal: maintain forward LVSV
- avoid bradycardia (even HR <80)
- avoid increases in SVR
- minimize myocardial depression
summary of anesthetic management of MS, MR, AS, AR
MS = slow, tight, full MR = fast, full, forward AS = normal & full AR = normal