Valvular heart disease Flashcards

1
Q

Types of murmurs

A

Systolic; ‘a systolic murmur, really tiring respiration’

  • AS: aortic stenosis
  • MR: mitral regurgitation
  • TR: triscuspid regurgitaton

Diastolic; ‘a regurg. makes SOB’

  • AR: aortic regurgitatoin
  • MS: mitral stenosis
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2
Q

How may breathing make murmurs louder?

A

On expiration = left-sided murmurs louder
- mitral, aortic
On inspiration = right-sided murmurs louder
- tricuspid
Valsalva manoeuvre = increase HOCM + mitral valve prolapse
- force exhalation against closed airway (pinch nose and breath out)

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3
Q

Aortic stenosis summary card

A

Narrowing of LV outflow at aortic valve
= age-related calcification, congenital bicuspid aortic valve, CTD, rheumatic heart disease
= O/E: BP w/ narrow pulse pressure, slow-rising pulse, palpable thrill (palpable heart murmur)
= EJECTION systolic murmur; ask pt to hold breath on expiration to accentuate murmur, can radiate to carotids and apex

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4
Q

Mitral regurgitation summary card

A

Backflow of blood from LV -> LA
= CTD, rheumatic heart disease, congenital
= O/E: normal/irregularly irregular pulse, palpatation, palpable laterally displaced apex beat
= PAN systolic murmur; louder on expiration as increased venous return from pulmonary veins to left heart, radiates to axilla

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5
Q

Triscuspid regurgitation summary card

A

Backflow of blood from RV -> RA
= infective endocarditis (?IVDU), rheumatic heart disease, CTD, congenital
= O/E: raised JVP, palpable parasternal heave, RHF signs - pleural effusion, hepatomegaly, ascites, pitting oedema
= PAN systolic murmur; ask pt to hold breath on inspiration to accentuate murmur (Carvallo’s sign)

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6
Q

Sx of valvular heart disease

A

Palpitations, SOB, syncope on exertion, heart failure signs, angina, orthopnoea

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7
Q

Ix findings for systolic murmurs

A

ECG
= AS; left axis deviation, enlarged R waves, T wave inversion
= TR; tall p-wave

CXR
= enlargement of ascending aorta
= AS; aortic valve calcification
= MR; cardiomegaly
= TR; right-sided enlargement
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8
Q

Aortic regurgitation summary card

A

Reflux of blood from aorta to LV
= infective endocartitis, rheumatic heart disese, congenital bicuspid aortic valve, dilation of aorta (HTN, aortitis)
= O/E: BP w/ wide pulse pressure, collapsing pulse (like a ‘water hammer’/Corrigan’s pulse), palpable displaced apex beat
= EARLY diastolic murmur; ask pt to sit forward and hold breath on expiration, radiates to carotids and apex

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9
Q

Mitral stenosis summary card

A

Narrowing of mitral valve, obstructing blood flow from LA -> LV
= infective endocartitis, rheumatic heart disese, congenital bicuspid aortic valve, dilation of aorta (HTN, aortitis)
= O/E: malar flush, ‘thready’/irregularly irregular pulse, palpable tapping apex, parasternal heave
= MID-diastolic murmur; loud first HS w/ opening snap, bell of stethoscope may be used

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10
Q

Ix findings for diastolic murmurs

A

ECG
= signs of LV hypertrophy
= MS; broad bifid p-waves, AF

CXR
= dilation of ascending aorta
= cardiomegaly

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11
Q

Which murmur belongs to which valvular problem?

a) Pan-systolic loudest on inspiration
b) Mid-diastolic
c) Ejection systolic
d) Pan-systolic loudest on expiration
e) Early diastolic

A

a) Tricuspid regurgitation
b) Mitral stenosis
c) Aortic stenosis
d) Mitral regurgitation
e) Aortic regurgitation

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12
Q

A 49-year-old woman presents with increasing shortness of breath on exertion developing over the past three months. She has no chest pain or cough, and has noticed any ankle swelling. On examination, blood pressure is 158/61mmHg, pulse is regular at 88 beats per minute and there are crackles at both lung bases. There is a diastolic murmur at the left sternal edge. What is the most likely diagnosis?

A. 	Aortic regurgitation 
B. 	Aortic stenosis 
C. 	Mitral regurgitation 
D. 	Mitral stenosis 
E. 	Tricuspid regurgitation
A

A. Aortic regurgitation

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13
Q

You see a 57-year-old woman who presents with worsening shortness of breath coupled with decreased exercise tolerance. She had rheumatic fever in her adolescence and suffers from essential hypertension. On examination, she has a murmur heard loudest over the mitral area. Which of the following is not a clinical sign associated with the most likely diagnosis?

A 	Malar flush 
B. 	Atrial fibrillation 
C. 	Pan-systolic murmur which radiates to axilla 
D. 	Tapping, undisplaced apex beat 
E. 	Right ventricular heave
A

C. Pan-systolic murmur which radiates to axilla

diagnosis is mitral stenosis

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14
Q

An 8 year old boy comes to the GP with his mother for a check-up. You find the child to be extremely sociable and friendly, with some mild learning difficulties. You also note distinct facial features including a broad forehead, short nose and full cheeks. On auscultation of his chest, you detect a murmur in the right 2nd intercostal space, loudest on expiration. What is the most likely diagnosis?

A. 	Hypertrophic Obstructive Cardiomyopathy
B.  	Infective endocarditis 
C. 	Aortic stenosis
D. 	Aortic regurgitation
E. 	Mitral stenosis
A

C. Aortic stenosis

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15
Q

Which of the following does not cause a systolic murmur?

A Atrial septal defect
B Ventricular septal defect
C Hypertrophic obstructive cardiomyopathy (HOCM)
D Aortic regurgitation
E None of the above
A

D Aortic regurgitation

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16
Q

You perform a cardiovascular examination on an elderly gentleman who reports episodes of collapsing and often wakes up short of breath at night.

Upon auscultation you discover an ejection systolic murmur, which radiates to the carotids.

Which is the most likely valvular pathology?

A Aortic stenosis
B Aortic regurgitation
C Mitral regurgitation
D Tricuspid regurgitation 
E Mitral stenosis
A

A Aortic stenosis

17
Q

A 53-year-old woman with Atrial Fibrillation is reviewed by her cardiologists.

On inspection the patients cheeks appear quite flushed. Auscultation reveals a very loud S1 and a mid diastolic murmur.

Which is the most likely valvular pathology?

A Mitral stenosis
B Graham Steele
C Mitral regurgitation
D Aortic regurgitation
E Austin Flint
A

A Mitral stenosis

  • Graham Steele is associated w/ pulmonary regurgitation
  • Austin Flint is associated w/ aortic incompetence
18
Q

49-year-old women presents with 3 month history of increasing SOB on exertion. She has no chest pain, cough or ankle swelling.

On examination: BP 158/61 and there are crackles at the bases of both lungs.

On auscultation you hear a diastolic decrescendo murmur loudest at the left sternal edge.

Which is the most likely valvular pathology?

A Aortic regurgitation
B Aortic stenosis
C Mitral regurgitation
D Mitral stenosis
E Tricuspid regurgitation
A

A Aortic regurgitation

19
Q

Which sign is commonly associated with a valvular condition where the murmur is heard louder during expiration, and softer during the Valsalva manoeuvre, and typically radiated to the carotid?

A Water hammer (collapsing pulse) 
B Flushed cheek (malar rash) 
C Displaced apex beat
D Slow-rising pulse
E Subcutaneous nodules
A

D Slow-rising pulse

diagnosis is aortic stenosis

20
Q

Narrow PP, heaving/thrusting undisplaced apex beat
Soft 2nd heart sound
ESM heard aortic area radiating to carotids

Diagnosis?

A

Aortic stenosis – exertional syncope, SOB, angina

21
Q

Displaced, volume overloaded apex beat (thrusting)
Soft 1st heart sound
Blowing PSM at apex radiating to axilla

Diagnosis?

A

Mitral regurgitation

22
Q

Wide pulse pressure
Displaced, volume overload apex beat
EDM at LSE – best heard leaning forward at expiration

Diagnosis?

A

Aortic regurgitation

23
Q

Tapping apex beat + malar flush
Loud 1st heart sound
Rumbling MDM at apex (louder in left lateral position at expiration)

Diagnosis?

A

Mitral stenosis

24
Q

PSM LLSE best heard at inspiration
L parasternal heave, pulsatile liver
Increased JVP to ear lobe, hepatomegaly, IVDU

Diagnosis?

A

Tricuspid regurgitation

25
Q

Low-pitched, rumbling, mid-diastolic murmur

A

Austin Flint murmur

= aortic regurgitation

26
Q

Mid-systolic click and end-systolic murmur at apex

A

Barlow murmur

= mitral valve prolapse

27
Q

Mid-diastolic murmur

A

Carey-Coombs murmur

= thickened mitral valve

28
Q

Continuous ‘machinery’ murmur

A

Gibson murmur

= patent ductus arteriousus

29
Q

High-pitched early diastolic murmur at upper left sternal edge

A

Graham-Steell murmur

= pulmonary regurgitation