Valacyclovir Flashcards
What is the primary action of Valacyclovir?
Valacyclovir is an antiviral medication that inhibits viral DNA synthesis.
True or False: Valacyclovir is only effective against bacterial infections.
False
List one indication for the use of Valacyclovir.
Treatment of herpes simplex virus infections.
What is a common adverse effect of Valacyclovir?
Nausea
Fill in the blank: Valacyclovir is contraindicated in patients with a history of __________.
hypersensitivity to the drug
Which virus is Valacyclovir commonly used to treat?
Herpes simplex virus
True or False: Valacyclovir can be used to treat shingles.
True
What is the mechanism of action of Valacyclovir?
It is converted to acyclovir in the body, which then inhibits viral DNA polymerase.
Name one drug interaction that may occur with Valacyclovir.
Probenecid
Short answer: How is Valacyclovir administered?
Orally
What is the recommended dosage adjustment for Valacyclovir in patients with renal impairment?
Dosage should be reduced based on creatinine clearance.
Which condition is NOT treated by Valacyclovir?
Influenza
True or False: Valacyclovir can be used for the prevention of cytomegalovirus infection.
True
What is an important consideration when prescribing Valacyclovir to elderly patients?
Increased risk of renal impairment and potential for adverse effects.
Fill in the blank: Valacyclovir should be used with caution in patients with __________.
dehydration
What is the brand name for Valacyclovir?
Valtrex
List one serious adverse effect of Valacyclovir.
Nephrotoxicity
True or False: Valacyclovir is effective against all strains of the herpes virus.
False
What should be monitored in patients receiving Valacyclovir?
Renal function
Fill in the blank: Valacyclovir may cause __________ in patients with a history of kidney problems.
acute kidney injury
What is the effect of food on the absorption of Valacyclovir?
Food does not significantly affect the absorption.
True or False: Valacyclovir can be used during pregnancy.
Caution is advised; consult a healthcare provider.
Name one pharmacokinetic property of Valacyclovir.
High bioavailability after oral administration.
What is the primary route of elimination for Valacyclovir?
Renal excretion
