Vaginal and Vulval Cancer Flashcards

1
Q

Who does vulval cancer generally present in?

How is this demographic changing?

How does it tend to present?

A

Elderly women

It is occurring more in women in their 30s/40s due to high risk HPV infection

An ulcer or mass associated with pain, itch, discharge or bleeding

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2
Q

What is the most common type of both vulval and vaginal cancer?

What can this often be co-existant with?

A

Squamous cell carcinoma

Cervical squamous cell carcinoma

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3
Q

Which particular strain of HPV is associated with causing vulval and vaginal cancers the most?

What is the precursor lesion for vulval cancer?

What is the precursor lesion for vaginal cancer?

What is another risk factor for vaginal cancer?

A

Type 16

Vulval intra-epithelial neplasia

Vaginal intra-epithelial neoplasia

Radiotherapy

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4
Q

What investigations are used for vulval cancer?

Where can vulval cancer spread to, that is the most important prognostic factor?

How is vulval cancer treated?

A

Vulval biopsy for diagnosis / CT/MRI for staging

Inguinal lymph nodes

Surgically - radical vulvectomy +/- inguinal lymphadenectomy

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5
Q

What is the most common cause of a tumour at the vagina?

When is the peak incidence of vaginal cancer?

What are some common presenting symptoms?

Where is the mass usually seen?

What is a very rare cause of a vaginal cancer, which may be seen as a polyp?

A

Metastases

60-70

Vaginal bleeding or discharge

Top of the vagina

Melanoma

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6
Q

What investigation should be done for vaginal cancer?

How is it treated?

A

Examination under anaesthetic and biopsy for diagnosis

Mainly with radiotherapy, radical surgery is only an option for stage 1 disease

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