Vagina Flashcards
What do you call the fibromuscular canal leading to the cervix?
vagina
the mucosa of the vaginal canal is lined by
non-keratinizing squamous epithelium
the lower 1/3 of the vagina is derived from the
urogenital sinus
the upper 2/3 of the vagina is derived from the
mullerian duct
the uterus, fallopian tubes, and cervix are derived from the
mullerian duct
what do you call focal persistence of columnar epithelium in the upper vagina?
adenosis
increased incidence of adenosis in what population?
females exposed to DES in utero
malignant proliferation of glands with clear cytoplasm in the vagina
clear cell adenocarcinoma
DES-associated vaginal adenosis can lead to
clear cell adenocarcinoma
what can DES exposure in utero do to the uterus
give it an abnormal shape
malignant mesenchymal proliferation of immature skeletal muscle; presents as bleeding and a grape-like mass protruding from the vagina or penis of a child (<5 yrs)
embryonal rhabdomyosarcoma
another name for embroil rhabdomyosarcoma
sarcoma botryoides
what is the characteristic cell of embryonal rhabdomyosarcoma
rhabdomyoblast
histologic feature of rhabdomyoblast
cytoplasmic cross-striations
immunohistochemical staining of rhabdomyoblast
+desmin
+myogenin