vaccines + syndromes

Question 1

What’s in the 6-in-1 vaccine?

Answer 1

diphtheria, tetanus, polio, whooping cough, hip + hep B

Question 2

When do you get the 6-in-1?

Answer 2

8 weeks, 12 weeks, 16 weeks

Question 3

When do you get the rotavirus vaccine?

Answer 3

8 weeks and 12 weeks

Question 4

When do you get pneumococcal vaccine?

Answer 4

12 weeks, 12 months

Question 5

When do you get men B?

Answer 5

8 weeks, 16 weeks, 12 months

Question 6

When do you get Men C?

Answer 6

12 months

Question 7

When do you get MMR?

Answer 7

12 months, 3/4 yrs

Question 8

What’s in 4-in-1 preschool booster?

Answer 8

diphtheria, tetanus, whooping cough + polio

Question 9

When do you get 4-in-1?

Answer 9

3-4 yrs

Question 10

What’s in 3-in-1?

Answer 10

tetanus, diphtheria, polio

Question 11

When do you get 3-in-1?

Answer 11

13-18 yrs

Question 12

when do you get men ACWY?

Answer 12

13-18 yrs

Question 13

8 weeks

Answer 13

6-in-1, rotavirus, men B

Question 14

12 weeks

Answer 14

6-in-1, rotavirus, PCV

Question 15

16 weeks

Answer 15

6-in-1, men B

Question 16

12 months

Answer 16

Hib/men C, MMR, PCV, men B

Question 17

3/4 yrs

Answer 17

4-in-1, MMR

Question 18

13-18 yrs

Answer 18

3-in-1, men ACWY

Question 19

12-13 yrs

Answer 19

HPV

Question 20

Downs syndrome complications

Answer 20

AVSD, ASD, VSD, PDA, TOF
hypothyroidism, leukaemia (ALL), Alzheimers
atlantoaxial instability
duodenal atresia, Hirschprung’s
glue ear + deafness
sub fertility
learning disabilities

Question 21

Downs syndrome features

Answer 21

trisomy 21
hypotonia, brachycephaly, short neck, short stature, flattened face + nose, single palmar crease, upward palpebral fissures, prominent epicanthic folds

Question 22

klinefelter

Answer 22

47 XXY
present at puberty
tall, wider hips, gynaecomastia, weak muscles, small testicles, reduced libido, shyness, infertility
breast cancer, osteoporosis, diabetes, anxiety + depression

Question 23

Turner’s

Answer 23

45 X0
short, webbed neck, high arching palate, downward sloping eyes, broad wide chest, cubits values, late puberty
CoA, AS, bicuspid AV, aortic dissection
hypothyroidism, recurrent otitis media, UTIs, osteoporosis, diabetes, LDs

Question 24

noonan syndrome

Answer 24

autosomal dominant
webbed neck, pacts excavatum, short, broad forehead, downward eyes, hypertelorism, low set ears
PS, hypertrophic cardiomyopathy, ASD
undescended testes, leukaemia + neuroblastoma

Question 25

fragile X syndrome

Answer 25

learning difficulties, macrocephaly, long face, long ears, macroorchidism
autism, ADHD, seizures, hypermobile joints

Question 26

Prader-Willi syndrome

Answer 26

hypotonia, hypogonadism, obesity, learning disability, fair skin, almond eyes, strabismus, thin upper lip, downturned mouth
infertility, behavioural problems

Question 27

Angelman

Answer 27

delayed development, learning disability, fascination with water, happy, inappropriate laughter, hand flapping, abnormal sleep, microcephaly, fair skin light hair, wide mouth with wide teeth
epilepsy, ADHD, ataxia

Question 28

William syndrome

Answer 28

short, LD, friendly extrovert, broad forehead, starburst eyes, flattened nasal bridge, long philtre, wide mouth with wide teeth, small chin
supravalvular AS, PS
ADHD, HTN, hypercalcaemia

Question 29

Patau

Answer 29

trisomy 13
microcephaly, small eyes, cleft lip/palate, polydactyl, scalp lesions
PDA, ASD, VSD

Question 30

Edwards

Answer 30

trisomy 18
micrognathia, low set ears, rocker bottom feet, overlapping of fingers
ASD, VSD, TOF, overriding aorta, CoA, hypo plastic left heart syndrome, oesophageal atresia, pyloric stenosis, Meckel diverticulum

Question 31

Pierre-Robin

Answer 31

micrognathia, posterior displacement of tongue, cleft palate
upper airway obstruction

Question 32

cri du chat

Answer 32

characteristic cry, feeding difficulties, LD, microcephaly, micrognathia, hypertelorism
severe cognitive, speech + motor disabilities
behavioural problems
excessive drooling, skin tags in front of eyes
ASD, VSD, PDA, TOF