vaccines Flashcards
What are the types of vaccines
live attenuated, inactivated, subunit, toxoid, recombinant
Which types of vaccines require boosters
inactivated non-living
What are the precautions for those with live vaccines
no preggo no infants no immunocompromised no within 28 days space 3-10 months apart from administration of antibody containing products
What is herd immunity
it is where those who are unable to get vaccinated are still protected from the disease as everyone around them are immune to it
what is a primary dose
single dose or a few doses
what is a booster dose
antibody concentration wanes over time so the booster dose will maintain protective levels of antibody
What are the 3 factors that reduce vaccine effectiveness
site vaccine is given
patient age and immune status
cold chain problems (not kept at appropriate temperatures)
what are some ADR
pain at injection site HA myalgia fever hematoma anaphylaxis, hypersensitivity
what are some contraindications
allergy to vaccine or components moderate or severe illness fever > 38 preggo (live vaccines) immunocompromised (live vaccines)
what is a precaution of vaccines
bleeding risk
which vaccines cannot be administered simultaneously or within the same day
pneumococcal conjugate vaccine and meningococcal conjugate vaccine in patients with functional or anatomical asplenia
4 week interval between the administration of the 2 vaccines to avoid interference of the meningococcal conjugate vaccine with PCV
how far apart must live vaccines be administered
IM or SQ must be spaced 28 days apart
what to do when there is a missed dose
the dose should be given ASAP. no need additional doses
what are the common components of vaccine
active components, adjuvants, antibiotics, stabilisers, preservatives, trace components
