Vaccinations Flashcards

1
Q

Which vaccinations are give subcutaneously?

Which vaccinations are live vaccinations?

A

Subcutaneous vaccines: MMR, varicella, IPV

Rotavirus, MMR, varicella are live vaccines

All vaccine given before 1 year are either killed or recombinant except for the rotavirus vaccine

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2
Q

Can live vaccinations be adminstered to HIV patients?

A

Yes.

MMR and varicella vaccines can be adminstered to an asymptomatic HIV infected patient

HIV patients should receive MMR and varicella vaccine at 12 months of age

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3
Q

Which vaccines can not be given to a pregnant adolescent?

A

Do not give MMR, varicella, intranasal influenza, HPV to pregnant adolescent

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4
Q

How many MMR vaccinations should a child at age 12 receive?

When should Tdap be adminstered?

When should meningococcal vaccination be adminstered?

A

Give 2 MMR vaccines by 12 years of age

Tdap is due at 11-12 years old, then Td every 10 years after

MCV4 given at 11-12 years with follow up boosters at 16 year

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5
Q

When is it not appropriate to adminster live vaccines?

A

Do not give live vaccines such as BCG, oral poliovirus, MMR, varicella vaccine to children with congenital defects of their immune function, children receiving immunosuppressive therapy, or children undergoing a bone marrow transplant

Do not give live virus or bacterial vaccines to a child receiving 2mg/kg or more of prednisone for longer than 14 days, children should be off high dose steroids for at least 3 months

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6
Q

Facts about the MMR vaccine

A

Measles vaccine may suppress tuberculin activity

If MMR and PPD are not given on the same day, will need to wait 6 weeks before giving the PPD

Varicella and MMR are given on the same day, or will need to wait 4 weeks apart

If a child has received any type of immunoglobulin, wait 3 months before giving the MMR or varicella vaccine

If the child has received a transfusion of packed RBC, must wait 5 months before giving MMR or varicella vaccine (6 months if given whole blood, 7 months if given plasma or platelets, 8 months if given IVIG for ITP, and 11 months if given IVIG for Kawasaki disease)

Post exposure within 72 hours prophylaxis with varicella or MMR vaccine is recommended to prevent disease

If MMR is given between 6 - 12 months as post exposure prophylaxis, the patient will still need to receive MMR series at 12 months and 4 years, prior to 6 months post exposure prophylaxis is immune globulins

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7
Q

Pneumococcal Vaccine

A

Give to high risk groups:

  • cochlear implants
  • cardiac or pulmonary disease
  • immunocompromised
  • long term steroid use

If patient is between 24 and 59 months who is not completely vaccinated for their age, just give one dose

If patient completed all series of PCV7 and are between 14 and 59 months old, then give one dose of PCV13

If the patient is at high risk, completed all series of PCV7 and is between 60 and 71 months old, then give 1 dose of PCV13

PCV 13 should be at least 8 weeks after the previous dose of PCV7

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8
Q

Meningococcal Vaccine

A

Vaccinate at 11-12 years old, then booster at 16 years old

For high risk patients such as complement deficiency or asplenia, give 2 doses at least 8 weeks apart, then 1 dose every 5 years after

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9
Q

Varicella

A

Two doses, first dose is 12-15 months, second dose is 4-6 years

Recommended minimum interval for those less than 13 years is 3 months

If older than 13 years, then wait 4 weeks between each dose

Make sure you vaccine children on low dose steroids, children with asthma, inhaled steroids, children of pregnant women

Do no vaccinate: in children with high dose steroids, greater than 2 mg/kg/day or pregnant adolescents

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10
Q

DTap/Tdap

A

Do not give children older than 7 years old DTap, give Tdap instead followed by Td for the remaining catch up doses and every 10 years

One Tdap once in your life, then get Td every 10 years

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11
Q

Hib

A

Vaccine is not effective against the nontypeable forms of Haemophilus that frequently cause otitis media and upper respiratory infections

Minimum age is 6 weeks

Hib is not recommended for those over 5 years except

  • high risk patients with sickle cell
  • leukemia
  • HIV
  • splenectomy
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12
Q

Hepatits A

A

Give to adolescent men who have sex with men

Adolescents who abuse IV drugs

Recommended for all children

Given at 1 year of age in 2 doses, 6 months apart

If hepatitis A exposure in household, give Hepatitis A vaccine as post exposure prophylaxis if over 1 years old, if less than 1 years old, give immunoglobulin

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13
Q

Rotavirus Vaccine

A

Minimum age of first dose is 6 weeks

Minimum interval between shots, 4 weeks

Prior to introduction of vaccine, most children were infected by age 5 years

Most common cause of gastroenteritis in infants and young children

If the child was not given an initial rotavirus vaccine by 15 weeks of age, then do not give it at all.

Do not administer the final dose of rotavirus if the child is greater than 8 months.

Do not give rotavirus to any children with a history of intussusception

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14
Q

Influenza Vaccine

A

Two types of influenza vaccine: inactivated and live attenuated vaccine

Live attenuated flu vaccine only in children greater than 2 years old and healthy

Can not use in pregnant adolescents and in girls 2-4 years old if they have been wheezing in the last 12 months

All children over than 6 months may get the flu vaccine

Children ages 6-23 months have increase risk of complications from flu

For children under 9 years old who have never been vaccinated with the Flu before, give at least 4 weeks apart x 2 for the first season

Intranasal flu vaccine can be given to healthy children greater than 2 years old, not for children with diabetes, asthma, or HIV

Do not vaccinate with the influenza vaccine if there was

  • severe reaction to previous vaccination
  • severe allergies to eggs
  • Guillain Barre syndrome within 6 weeks of getting flu vaccine
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15
Q

HPV

A

Covers types 6, 11, 16 and 18 boys and girls 9 to 26 years old

Give at 0, 2, and 6 month intervals

Can increase risk of syncope after vaccination. Recommended to observe patients for 15 mins after vaccination

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16
Q

Hepatitis B

A

Give Hepatitis B vaccine prior to 12 hours after birth if the mother is HBsAg+ or unknown status.

Give Hepatitis B immune globulin to the infant born to a HBsAg+ mother within 12 hours.

Preterm infants with birth weight less than 2 kg can be given the Hepatitis B vaccine at 1 month of age if mother is HBsAg negative, if +, then Hep B must be given and not counted in the required 3 dose series.

Infants born to mothers with HBsAg+ should be tested after vaccination series for anti-HBs and HBsAg at 9 months.

Catch up Against Hepatitis B:

  • under 11 years old, give 3 doses
  • Older than 11 years old, 2 doses 4 months apart
17
Q

What are the contraindications to vaccination?

A

Seizure after 1 day after previous DTap, the seizure odes not cause neurologic damage or epilepsy

Do no revaccinate DTap if there is a history of encephalopathy within 7 days of vaccine
No MMR if they are pregnant or if there is immunodeficiency, except healthy HIV pts

Anaphylaxis to vaccine

  • Egg antigens: Influenza, yellow fever
  • Streptomycin, neomycin, and polymyxin B: IPV
  • Neomycin: MMR, varicella
  • Gelatin: MMR, varicella, yellow fever