Vaccinations Flashcards
Inactivated vs live vaccine?
Live have more contraindications and can only be given when healthy; inactivated can be used in pregnant, immunosuppressed, severe illness, recent blood transfusion
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What is a conjugate vaccine?
covalently attaching a polysaccharide antigen to a carrier protein, thereby conferring the immunological attributes of the carrier on the attached antigen
Possible contraindications to getting a vaccination
allergy to component, encephalopathy, pregnancy, immunosuppression, severe illness, recent blood products
Which vaccines are live vaccines?
MMR, Varicella, Rotavirus, intranasal Influenza
Why is Diphtheria vaccine given?
mortality
Why is Tetanus vaccine given?
mortality
Why is Pertussis vaccine given?
death by secondary infections
Why is Polio vaccine given?
95% asx; 1-2% aseptic meningitis; < 1% flaccid paralysis; mortality
Why is H-flu B (Hib) vaccine given?
leading cause of bacterial meningitis; mortality especially in young
Why is Measles vaccine given?
pneumonia (most common), acute encephalitis (rare); mortality
Why is Mumps vaccine given?
orchitis may lead to infertility
Why is Rubella vaccine given?
transplacental damages of fetus
organ damage and fetal death
congenital rubella syndrome
Why is Varicella vaccine given?
morbidity, contagious, inconvenience
Why is Herpes Zoster vaccine given?
morbidity
Why is Hep A vaccine given?
children asx and are vectors for adult infection
