Vaccination Schedule Flashcards
What can be used in inactivated vaccines?
Inactivated virus Inactivated toxins Surface proteins Polysaccharide Conjugated polysaccharide (polysaccharide attached to protein)
How do inactivated vaccines work?
First dose - body produces IgM and some IgG against antigens - primary response
Second dose - body produces mainly IgG against antibodies - secondary response - boosts immunity
What is used in live attenuated vaccines?
Viruses which have been altered so do not cause disease
How to live attenuated vaccines work?
Viruses replicated in the host and the host’s immune system responds as it normally would to infection
What adverse effects can follow DTaP/IPV/Hib vaccine and when?
48 hours
Local reaction and fever
What adverse effects can follow MMR vaccine and when?
7-10 days
Rash and fever
3 weeks
Parotitis
What does DTaP/IPV/Hib protect against and what type of vaccine is it?
Diptheria - toxin Tetanus - toxin Pneumococcal - inactivated whole cell Polio - inactivated virus Haemophilus influenza B - conjugated polysaccharide
What does PCV protect against and what type of vaccine is it?
Pneumococcal disease - polysaccharide
What does Rotarix protect against and what type of vaccine is it?
Rotavirus - live attenuated
What do MenB, MenC and MenACWY protect against and what type of vaccine are they?
Meningococcal disease B
Meningococcal disease C
Meningococcal diseases A, C, W and Y
Conjugated polysaccharide
What does MMR protect against and what type of vaccine is it?
All live attenuated
Measles
Mumps
Rubella
What does LAIV (fluenz tetra) protect against and what type of vaccine is it?
Influenza virus
Live attenuated
What does Gardasil protect against and what type of vaccine is it?
Human papilloma virus
Inactive - viral coat protein
What does Zostavax protect against and what type of vaccine is it?
Herpes zoster
Live attenuated
When is DTaP/IPV/Hib given?
2 months
3 months
4 months