Vaccination Schedule Flashcards
What can be used in inactivated vaccines?
Inactivated virus Inactivated toxins Surface proteins Polysaccharide Conjugated polysaccharide (polysaccharide attached to protein)
How do inactivated vaccines work?
First dose - body produces IgM and some IgG against antigens - primary response
Second dose - body produces mainly IgG against antibodies - secondary response - boosts immunity
What is used in live attenuated vaccines?
Viruses which have been altered so do not cause disease
How to live attenuated vaccines work?
Viruses replicated in the host and the host’s immune system responds as it normally would to infection
What adverse effects can follow DTaP/IPV/Hib vaccine and when?
48 hours
Local reaction and fever
What adverse effects can follow MMR vaccine and when?
7-10 days
Rash and fever
3 weeks
Parotitis
What does DTaP/IPV/Hib protect against and what type of vaccine is it?
Diptheria - toxin Tetanus - toxin Pneumococcal - inactivated whole cell Polio - inactivated virus Haemophilus influenza B - conjugated polysaccharide
What does PCV protect against and what type of vaccine is it?
Pneumococcal disease - polysaccharide
What does Rotarix protect against and what type of vaccine is it?
Rotavirus - live attenuated
What do MenB, MenC and MenACWY protect against and what type of vaccine are they?
Meningococcal disease B
Meningococcal disease C
Meningococcal diseases A, C, W and Y
Conjugated polysaccharide
What does MMR protect against and what type of vaccine is it?
All live attenuated
Measles
Mumps
Rubella
What does LAIV (fluenz tetra) protect against and what type of vaccine is it?
Influenza virus
Live attenuated
What does Gardasil protect against and what type of vaccine is it?
Human papilloma virus
Inactive - viral coat protein
What does Zostavax protect against and what type of vaccine is it?
Herpes zoster
Live attenuated
When is DTaP/IPV/Hib given?
2 months
3 months
4 months
When is rotarix given?
2 months
3 months
1 year
When is PCV given?
2 months
4 months
1 year
When is MenB given?
2 months
4 months
When is MenC given?
3 months
1 year
When is MMR given?
1 year
3 years 4 months
When is Hib/MenC given?
1 year
When is DTaP/IPV given?
3 years 4 months
When is LAIV given?
Yearly from 2y-17y
When is gardasil given?
Females aged 12/13 - 2 doses 6 months apart
When is DTaP alone given?
14 years
When is MenACWY given?
14 years
When is inactivated influenza given?
Yearly for over 65s
When is zostavax given?
70y
What immunisations are given at 2 months?
DTaP/IPV/Hib
PCV
Rotarix
MenB
What immunisations are given at 3 months?
DTaP/IPV/Hib
Rotarix
MenC
What immunisations are given at 4 months?
DTaP/IPV/Hib
PCV
MenB
What immunisations are given at 1 year?
Hib/MenC
PCV
Rotarix
MMR
What immunisations are given at 3 years 4 months?
MMR
DTaP/IPV
What immunisation is given yearly from 2y-17y?
LAIV
What immunisation is given to girls aged 12/13y?
Gardasil
What immunisations are given at 14 years?
DTaP
MenACWY
What immunisation is given yearly over 65?
Inactivated influenza
What immunisation is given once at age 65?
Pneumococcal
What immunisation is given at age 70?
Zostavax
