Vaccination Flashcards
if vaccine is given first, when can we give antibody?
after 2 weeks
If antibody is given first, how many months should we wait before giving vaccine?
3 months
Vaccine interval between active immunization with MMR, MMRV or Varicella and packed RBCs
6 months
Vaccine interval between active immunization with MMR, MMRV or Varicella and whole blood
6 months
Vaccine interval between active immunization with MMR, MMRV or Varicella and Botulinum Ig
6 months
Vaccine interval between active immunization with MMR, MMRV or Varicella and CMV IVIg
6 months
Vaccine interval between active immunization with MMR, MMRV or Varicella and HBIg
3 months
Vaccine interval between active immunization with MMR, MMRV or Varicella and tetanus prophylaxis
3 months
Vaccine interval between active immunization with MMR, MMRV or Varicella and IVIg for Kawasaki disease
11 months
Vaccine interval between active immunization with MMR, MMRV or Varicella and IVIg for ITP
400mg/kg : 8 months
800 - 1000mg/kg : 10 months
All vaccines can be given simultaneously except for
PCV 13 and Menactra
PCV 13 and PPSV23
interval between 2 live parenteral vaccine, or live intranasal vaccine
4 weeks
If less than 4 weeks, repeat the second vaccine given
Can 2 live vaccines administered via oral route be given simultaneously?
yes! may be given at any time before or after each other
Timing of 2 live vaccines
only applicable if either vaccine was given ALONE
- MMR1 given < 4days to second dose of MMR is VALID
- MMR and Varicella < 4 days to second dose of MMR is NOT VALID
- MMRV <4 days to second dose of MMRV is NOT VALID
Interval between doses of same vaccine
- doses should not be given earlier than minimum age
- vaccine doses given 4 days before minimum interval is VALID
- doses administered up to 4 days before the minimum interval or age can be counted as valid
Contraindications and precautions to vaccine:
allergy to component
Live and Inactivated vaccines are contraindicated
Contraindications and precautions to vaccine:
pregnancy
live vaccines contraindicated
Inactivated: vaccinate if indicated
Contraindications and precautions to vaccine:
Immunosuppression
Contraindicated in live vaccines
Inactivated vaccines: vaccinate if indicated
deferred during pregnancy
HPV vaccine
Permanent contraindications to vaccines
- severe allergic reaction to a vaccine component
- encephalopathy not due to another identifiable cause occurring within 7 days of pertussis vaccine
- SCID (rotavirus)
- history of intussusception (rotavirus)
- GBS occurring 6 weeks or more after previous dose of tetanus toxoid or influenza vaccine
- thrombocytopenia (MMR)
- chronic GI disease, spina bifida, bladder exstrophy (rotavirus)
Temporary precautions to vaccine
- history of Arthus type hypersensitivity after prev dose of diphtheria or tetanus toxoid
- progressive neurologic disorders including infantile spasms, uncontrolled epilepsy, progressive encephalopathy
when can we vaccinate patients who will be undergoing immunosuppression?
Live vaccines: more than or equal to 4 weeks before immunosuppression
Inactivated vaccines: more than or equal to 2 weeks prior to immunosuppression
vaccines that are prepared in eggs hence may cause anaphylaxis to patients with allergies to eggs
*Redbook (p.47) Yellow Fever & Influenza Vaccines prepared in eggs contain egg proteins and, on rare occasions, may induce immediate allergic reaction including anaphylaxis. Skin Testing may be done prior to vaccination.
Arthritis after MMR vaccination is due to
Rubella component
