v2 Flashcards
Which one of the following lesions usually presents as a discrete, freely movable nodule in the breast?
A. sclerosing adenosis
B. cystic disease
C. ductal carcinoma
D. fibroadenoma
E. plasma cell mastitis
D. fibroadenoma
.Bleeding from the nipple in a 45-year-old woman, without a palpable breast mass should suggest :
A. fibroadenoma
B. sclerosing adenosis
C. fat necrosis
D. intraductal papilloma
E. chronic cystic mastitis
D. intraductal papilloma
- Which of the following is the most likely cause of a bleeding nipple?
A. duct papilloma
B. fat necrosis
C. galactocele
D. breast cancer
E. fibroadenoma
A. duct papilloma
. A 65 year old female presents with fever, headache and diplopia. On palpation, tenderness is noted along the course of the
temporal artery. A biopsy would most likely confirm which of the following diagnosis?
A. Takayasu arteritis
B. Retinoblastoma
C. Giant cell arteritis
D. Kaposi sarcoma
C. Giant cell arteritis
.A 13 year old boy was brought to the ER due to progressive weakness, easy fatigability and weight loss for the past 4 months . In addition, he has recently presented with nausea, vomitingand abdominal discomfort. On PE his blood pressure was noted to be markedly decreased, in addition there was note of increased pigmentation over the creases of his skin. What is the most likely diagnosis of this case?
1- Osteitis fibrosa cystica
2- Secondary hyperaldosteronism
3- Cushing syndrome
4- Addison disease
4- Addison disease
50 year old male chronic smoker presents with chronic cough dyspnea and sputum production. He also has bouts of easy fatigability. Patient also presents with increased anteroposterior diameter of the chest wall. Patient most likely has this type of
emphysema
1- Centriacinar
2- Paraseptal
3- Panacinar
4- Alveolar
1- Centriacinar
The presence of Heinz bodies and bite cells in a patient having hemolytic anemia strongly suggests:
1- G6OD Deficiency
2- Alpha thalassemia
3- Multiple myeloma
4- Sickle cell anemia
1- G6OD Deficiency
8.A 23-year-old woman consults an obstetrician because of the onset of vaginal bleeding in what she considers to be the fifth month of pregnancy; however, examination reveals the uterus to be enlarged to the size of a 7-month pregnancy. Intravaginal ultra sound fails to detect a fetal heartbeat and instead shows a “snowstorm pattern.” HCG is markedly elevated. These findings are strongly suggestive of
1- Preeclampsia
2- Eclampsia.
3- Placenta accreta
4- Ectopic pregnancy
5- Hydatidiform mole
5- Hydatidiform mole
A 32-year-old woman presents with amenorrhea, galactorrhea, and visual field defects, all of several months’ duration.
Magnetic resonance imaging reveals a hypophyseal mass impinging on the optic chiasm. This is most likely a
a. prolactinoma.
b. somatotropic adenoma
c. corticotropic adenoma.
d. craniopharyngioma
a. prolactinoma.
- 80 year old patient, previously healthy woman feels a lump in her right breast. The physician palpates a 2.5-cm firm mass
in the upper outer quadrant. Nontender right axillary lymphadenopathy is present. A lumpectomy with axillary lymph node
dissection is performed. Microscopic examination shows that the mass is an infiltrating ductal carcinoma. Three of 10 axillary
nodes contain metastases. Flow cytometry on the carcinoma cells shows a small aneuploid peak and high S-phase.
Immunohistochemical tests show that the tumor cells are positive for estrogen and progesterone receptor (ER/PR), negative
for HER2/neu expression, and positive for cathepsin D expression. What is the most important prognostic factor for this
patient?
a. Lack of HER2/neu expression in the carcinoma
b. Histologic subtype of carcinoma
c. Expression of stromal proteases in the carcinoma
d. Presence of lymph node metastases
e. Age at diagnosis
f. DNA content in the carcinoma
g. Estrogen receptor positivity
d. Presence of lymph node metastases
A 4-year-old child from China was brought to the pediatrician due to fevers lasting 5 days. fever is unresponsive to
acetaminophen. Physical examination shows the desquamation of the skin on fingers, as well as edema of the hands and feet.
The patient has bilateral conjunctival injection, cervical lymphadenopathy, erythema of the tongue. Immediate treatment with
Aspirin and intravenous immunoglobulin was started to avoid which of the following complications?
A. Buerger disease
B. Takayasu arteritis
C. Kawasaki disease
D. Polyarteritis nodosa
E. Behcet disease
C. Kawasaki disease ( cornory arteray anuresum )
. A 27-year-old man who is an IV drug user presents to the emergency department because of abdominal pain. He reports
red discoloration of his urine. On examination, he is hypertensive and has no dyspnea, chest pain, or hemoptysis. After initial
evaluation in the clinic, the patient is admitted to the hospital. A chest radiograph and radiographic imaging of the kidneys,
bladder, and pelvis reveal no abnormalities. Laboratory studies reveal elevated levels of amylase and lipase and an elevated
level of creatinine. The patient is positive for hepatitis B surface antigen. Which of the following is the most likely diagnosis?
A. Polyarteritis nodosa
B. Kawasaki disease
C. Goodpasture syndrome
D. Acute pancreatitis
A. Polyarteritis nodosa *30 % important for dignosis
Malignant neoplasm of melanocytes; most common cause of death from skin Cancer and risk of metastasis,
driven by activating mutation in BRAF kinase ,we have types :
1- Acral lentiginous : on the palms or soles for dark-skinned individuals ,Not related to UV light exposure.
2- Superficial spreading Most common subtype
3- Lentigo maligna: on face
4- Nodular : elevate the epidermis
2- Superficial spreading Most common subtype
sebrrohic keratosis
lesions with high keratocytes.,Greasy appearance, mostly in elderly, sharply demarked lesion, coin-like
lesions. NOT harmful.
Basel cell carcinoma:
Most common skin cancer,malignant but it does not metastasis. in Elderly. Shiny palpules-nose and
upper lips.Highly vascularised.
