Uworld Flashcards

1
Q

Describe frostbite

A

Is characterized by freezing of tissue, leading to disruption of cell membranes, ischemia, vascular thrombosis and inflammatory changes.

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2
Q

How should Mefloquine treatment be given as chemoprophylaxis in traveling to chloroquine resistance endemic areas?

A

Begin >= 2 weeks prior to travel, continued during stay and discontinued 4 weeks after returning.

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3
Q

Parkinson disease commonly presents initially with the classic tetrad of ____

A

Resting tremor
Postural instability
Bradykinesia
Rigidity

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4
Q

Classic reactive arthritis consists of a triad of

A

Nongonococcal urethritis
Oligoarthritis
Conjunctivitis

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5
Q

What is myoclonus?

A

Myoclonus is characterized by sudden, involuntary muscle contraction or relaxation that results in movement of limbs or joints.

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6
Q

Posthypoxic myoclonus is often seen after _______

A

Cardiac arrest

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7
Q

Posthypoxic myoclonus acute form- myoclonus status epilepticus occurs while patients are ________ and is characterized by __________

A

Still unconscious

Generalized (often symmetric) myoclonus that involves the axial, limb and facial muscles.

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8
Q

What is a hydrocele

A

Hydrocele is a fluid collection within the tunica vaginalis, a sac surrounding the testis

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9
Q

____________ is the most frequent bacterial cause of Lemierre syndrome

A

Fusobacterium necrophorum

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10
Q

_____________ is caused by an oropharyngeal infection, usually pharyngitis or tonsillitis that leads to local invasion of the lateral pharyngeal wall and infection of the neurovascular bundle especially the internal jugular vein

A

Lemierre syndrome

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11
Q

Evidence-based maintenance monotherapy options for bipolar disorder include ________, ________, _________ and ___________

A

Lithium, valproate, quetiapine and lamotrigine

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12
Q

In bipolar patients with severe and frequent mood episodes, the combination of _________ and _________ is used as first line combination pharmacotherapy.

A

Lithium or valproate and a second generation antipsychotic

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13
Q

Neoplastic cells travel through the vasculature and lodge in the small- caliber vessels at the ___________

A

Gray and white matter junction

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14
Q

Manifestation of metastatic brain disease in a patient with lung cancer includes: _________, __________, _____________ and _________

A

Headaches, focal deficit, cognitive changes and seizures

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15
Q

Cocaine intoxication typically presents with _______, ________ and _________

A
  • Elevated blood pressure and heart rate
  • Feelings of euphoria
  • Increased alertness
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16
Q

More life threatening consequences of cocaine intoxication include _______ and _____

A

Cardiac ischemia and intracranial hemorrhage

17
Q

Phencycline poisoning can present with _________, ________ ________, ___________ and often ________

A

Agitation, miosis, tachycardia, nystagmus and often psychotic and/or dissociative behavior

18
Q

__________ most commonly present with severe headache that is not relieved by nonsteroidal anti-inflammatory drugs.

A

Brain abscesses