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Uworld Flashcards

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1
Q

Most common cause of aseptic meningitis

A

Enteroviruses

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2
Q

Specific sign of left sided heart failure

A

Orthopnea

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3
Q

Specific sign for right sided heart failure

A

Bilateral lower Extremity edema

Congestive hepatomegaly

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4
Q

Prolonged PT in HBV

A

Poor prognosis

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5
Q

Wernicke encephalopathy

A

Ataxia, nystagmus, ophthalmoplegia, anterograde amnesia

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6
Q

Korsakoff psychosis

A

Anterograde and retrograde amnesia, apathy, lack of insight, confabulation

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7
Q

Flutamide

Mechanism of action

A

Impaired androgen - receptor interaction

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8
Q

Prostacyclin

A

Inhibits platelet aggregation and adhesion
Vasodilates
Increase vascular permeability
Stimulates leukocyte chemotaxis

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9
Q

Hand foot mouth disease

A

Vesicular lesions on the buccal mucosa, tongue, and soft palate

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10
Q

HSV gingivostomatitis

A

Swollen gums, vesicular lesions on the lips and hard palate

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11
Q

Very few v cholerae organism are needed to cause disease when:

A

Achlorhydria

Omeprazole

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12
Q

Kiesswlbach plexus

A

NASAL SEPTUM
Ant ethmoidal artery
Sphenopalatine artery
Superior labial artery

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13
Q

Lyme disease

A

1 flu like, erythema chronicum migrans
2 AV block, facial palsy
3 joint arthritis, encephalopathy

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14
Q

DOC for Raynaud disease, vasospasm, pallor, cyanotic extremities

A

Nifedipine

Pines for vasospasm

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15
Q

Drug for stable angina

A

Verapamil, diltiazem

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16
Q

Blotchy red muscle fibers on Gomori trichrome stain

A

Mitochondrial myopathies

17
Q

Tachyphylaxis

A

Nitroglicerine
Dopamine
Alpha agonist: phenylephrine, xylometazoline, oxymetazoline

18
Q

Lithium induced nephrogenic DIabetes insipidus

A

Amiloride

19
Q

Nephrogenic diabetes insipidus treatment ?

A

Loop diuretics

20
Q

Hyperglycemic drugs

A

Diazoxide, thiazides

21
Q

Dernatomyositis

Related malignancies ?

A

Lung
Colorectal
Ovarian

22
Q

Selective muscarinic antagonists

A

Glycopyrrolate
Hyoscyamine
Propantheline

23
Q

Tricyclic antidepressants

Cardiotoxicity by 4 mechanism :

A

Torsades
M block
Alpha block
Blocking the reuptake of NE

24
Q

Lead poisoning

A

Microcytic sideroblastic anemia
⬇️ heme synthesis
⬆️ delta-ALA in plasma
⬆️ protoporphyrin

25
Q

Drugs that ⬆️ Neural tube defect

A

Methotrexate
TMP-SMX
Valproate

26
Q

Anticipation

A

Fragile X syndrome
Myotonic dystrophy
Friedreich ataxia

27
Q

Chronic lymphedema is a risk factor for the development of

A

Cutaneous angiosarcoma also known as Stewart-Treves syndrome

28
Q

Drugs that should be avoided w/ hypertrophic cardiomyopathy

A

VASODILATORS

DIURETICS

29
Q

Venodilators

A

⬆️peripheral venous capacitance
⬇️cardiac preload
⬇️LVEDP

30
Q

Metalloproteinases

A

Zn containing enzymes that degrade components of the ECM and basement membrane

UWorld (5 decks)

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