UWorld 3 Flashcards
intrauterine fetal demise (IUFD)
-fetal death at >20 weeks
-diagnosis: absence of fetal cardiac activity on US (dec or absent fetal movement)
-management:
20-23 weeks: dilation and evacuation or vaginal delivery
>24 weeks: vaginal delivery
complication: coagulopathy after several weeks of fetal retention
evaluation of fetal demise
fetal: autopsy, gross and microscopic exam of placenta (eval for signs of abruption or infection), membranes, cord; karyotpye/genetic studies
maternal: Kleihauer-Betke test for fetomaternal hemorrhage; antiphospholipis Ab; coagulation studies (for h/o recurrent pregnancy loss, fhx or personal h/o venous thrombosis, fetal growth restriction)
Primary infertility
- inability to conceive after a year of unportected sex in nulliparous pt <35yo
- hysterosalpingogram is used to diagnose an anatomic cause of infertility such as tubal obstruction from prior pelvic infection
congenital aromatase deficiency
- rare enzyme deficiency that prevents conversion of androgens to estrogens=undetectable estrogen levels
- causes virilization of female fetuses–>nml internal genitalia with ambiguous external genitalia
McCune-Albright syndrome
- triad: cafe au lait spots, polyostotic fibrous dysplasia, autonomous endocrine hyperfunction
- most common ft: gonadotropin-independent precocious puberty=early puberty
CAH (21) CP
- at birth: ambiguous external genitalia and nml internal female reproductive organs (uterus, ovaries)
- electrolyte abnormalities (hyponatremia)
Bartholin duct cyst
- common in women <30yo
- duct obstruction causes fluid accumulation, gland distension=cyst
- soft, mobile, nontender cystic mass is usually asymptomatic and found at base of labium majus
- if asymptomatic, observation is recommended
(symptomatic: treat like an abscess, with incision and drainage, followed by placement of a word catheter)
Mittelschmerz
- physiologic cause of unilat abdo pain in young women
- pain occurs in the middle of the menstrual cycle (days 10-14) corresponding with time of ovulation
- reassurance is indicated once acute path is excluded
Differential diagnosis of dysmenorrhea
- primary dysmenorrhea: crampy lower abdo and back pain during menses
- endometriosis: pain peaks before menses, dyspareunia, infertility
- fibroids: heavy menses with clots; constipation, urinary frequency, pelvic pain/heaviness; enlarged uterus on exam
- adenomyosis: dysmenorrhea, pelvic pain, menorrhagia, bulky globular and tender uterus
- pelvic congestion: dull and ill defined pelvic ache that worsens with standing
pubic symphysis diastasis
RF:
-fetal macrosomia, multiparity, precipitous (traumatic) labor, operative vag delivery
CP:
-difficulty ambulating/weight-bearing, radiating suprapubic pain, pubic symphysis tenderness, intact neuro exam
Management:
-conservative, NSAIDs, physical therapy, pelvic support
Hydatidiform mole
CP:
- abnml vaginal bleeding +/- hyropic tissues
- uterine enlargement>gestational age
- abnormally elevated beta-hcg levels
- theca lutein ovarian cysts
- hypermesis gravidum
- preeclampsia with severe features
- hyperthyroidism
RF:
- extremes of maternal age
- h/o hydatidiform mole
Diagnosis:
- snowstorm on US
- quantitative beta-hcg
- histologic eval of uterine contents
Management:
- dilation and suction curettage
- serial serum beta-hcg post evacuation
- contraception for 6 mo
Initial painful lesion
chancroid, genital herpes
chancroid
- haemophilus ducreyi
- multiple and deep ulcers
- base may have gray to ylw exudate
- organism clump: “school of fish”
genital herpes
- multiple small grouped ulcers
- shallow with erythematous base
- multinucleated giant cells and intranuclear inclusions (Cowdry type A)
granuloma inguinale (donocanosis)
- klebsiella granulomatis
- ectensive and progressive ulcerative lesions without LAD
- base may have granulation-like tissues
- deeply staining GN intracytoplasmic cysts (donovan bodies)