Uworld Flashcards

1
Q

Cistic fibrosis bacterias

A

Haemofilus influenzae
S aureus
Pseudomona
Burkholderia cepacia

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2
Q

CYSTIC FIBROSIS

A

TRANSMEMBRANE CONDUCTANMCE DEFECT
ABSENT VAS DEFERENT
DIGITAL CLUBBING
NEUMONIAS-SINUSISTIS
CIRROSIS BILIAS
PANCREATITIS
DIABETES
DEFICIENCIA VIT ADEK

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3
Q

IMPAIR IN NEUTROPHIL FREE RADICAL FORMATION

A

CHRONIC GRANULOMATOSIS DISEASE
ASPERGILUS
S AUREUS
CATALASA POSITIVOS

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4
Q

INCREASE OF DEAD SPACE (LUNG DISEASE)

A

TEP
ENFISEMA
ARDS

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5
Q

Minuto ventilacion

A

Volumen tidal X Fr

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6
Q

Shalow breating index

A

Weaned off the ventilator

Respiratory rate/ tidal vollow index = high tidal vol = efficient breath

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7
Q

Neumonia y absceso cerebral

A

Nocardia

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8
Q

Silicosis xq es suceptible a TB

A

Impair macrophage function
Silica disrup fagolisosoma

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9
Q

Test de broncoprovacion en asma? Medicacion

A

Metacholine (muscarinico colinergico agonista) induce broncocontriccion

Inhalar y hacer espirometria seriada…pcted con asma tiene hiperespuesta y disminuye la FEV1 a dosis bajas que en aquellos sin asma

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10
Q

Teofilina

A

Inhibidor de las fosfodiesterasa 3 tto asma refracftaria

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11
Q

Miastenia gravis tto

A

AC contra receptores nicotinicos acetilcolina en la membrana post sinaptica

Tto. Piridostigmina, neostigmina

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12
Q

Bromuro de ipratropio accion

A

Anticolinergico derivado de la atropina (bloquea la acetilcolina) blolquea accion parasimpatica en las glandulas submucosas traqueobronquial

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13
Q

Anaerobios (cavidad oral)

A

Prevotella
Fusobacterium
Peptostreptococo

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14
Q

Elastina

A

Composed of nonpolar amnioacids glicina alanina vakina prolina lisina

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15
Q

Neumonitis en lung transplant

A

Citomegalovirus enveloped double DNA
Profilaxis : valganciclovir

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16
Q

Enveloped single ARN virus

A

Influenza

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17
Q

Enveloped single ARN virus

A

Influenza

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18
Q

Nonenveloped single ARN virus

A

Rhinovirus

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19
Q

Nonenveloped doble DNA

A

ADENOVIRUS

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20
Q

Granulomas (mediadores) de

A

Cd4
TNF ALFA
INTRERFERON GAMMA

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21
Q

EPIDERMAL GEOWTH FACTOR RECEPTOR MUTATION

A

NON SMALL CELL LUNG CANCERS
MOST COMMON ADENOCARCINOMA IN NON SMOKERS

22
Q

GLIAR FIIBRILLARY ACIDIC PROTEIN POSITIVE

A

ASTROCYTOMA

23
Q

KRAS MUTATION

A

25% ADENOCARCIONA ASSOCIATED WITH SMOKERS

COLORECTAL CA
PANCREATIC CA

24
Q

MUCIN GEN OVEREXPRESSED

A

BREAST CA
NON SMALL CELL LUNG CA
PANCREATIC CA

25
Q

VIMENTIN

A

SARCOMA

26
Q

Virulence facto haemophilus

A

Capsule composed by polyribosylribitol

27
Q

Zidovudin prevent fetal transmision HIV

A

Nucleoside reverse transcriptase inhibitors

Block phosphodiester bond formation

28
Q

Tto CMV

A

Ganciclovir

29
Q

Tto para CMV no requiere activacion intrcelular

A

Foscarnet

30
Q

Squamous cell carcinoma orofaringe y nasofaringe

A

Orofaringe ➡️ HOV
NASOFARINGE➡️ epstein bar

31
Q

Meningitis

A

Neumococo
Meningococo
Haemopihilus
E coli
Streptococcus b

Listeria➡️ resist a cefalosporina…..añadir ampicilina

32
Q

LCR HEMORRAGIC , LYMPHOCYTIC, PLEOCYTOSIS, increased protein norml glucose

A

Herpes

33
Q

P vivax y ovale infect rbc

A

Young , large

34
Q

P. Malaria infects rbc

A

Erythrocyted have been for month inblood

35
Q

P. Malaria infects rbc

A

Erythrocyted have been for month inblood

36
Q

Bacterias con IGA proteasas

A

Gonoco
Neumococo
Haemofilus

37
Q

Bacterias que requieren opsonizacion y fagocitosis

A

Bact encapsuladas
Neumococo
Meningococos
Haemofilus

38
Q

Abacavirvih

A

8% hypersensitivity reaction asociated to HLA B 57

39
Q

Jarisch Herxheimer reaction

A

6-8 hrs after tto sifilis
Lyme
Leptospira
Bartonella

40
Q

Aciclovir action

A

Guanosine analog …fosforilado por virus de herpes via timidine kinase a aciclovir monofosfato

41
Q

LCR LIMPHOCYTIC PLEIOCITOSIS WITH NO ORGANISM

A

Arboviral ➡️west nile,st louis ,la crosse

42
Q

Lipid soluble hormone

A

Thyroid
Steroid (
Estrogen,aldosterone,cortisol)

43
Q

Non lipid soluble hotmone

A

ACTH
ADH
EPINEPHRINE INSULINE

44
Q

Tiamina cofactor de. Que enzimas ?

A

BRANCHED CHAIN KETOACID DEHYDROGENASE
ALFA KETOGLUTARATE DEHYDROGENASE (TCA)
PYRUVATE DEHYDROGENASE (GLICOSISIS TO TCA)
TRANSKETOLASE (HMP SHUT)

45
Q

PYRIDOXINE COFACTOR DE

A

TGO-TGO
DECARBOXYLATION REACTIONS
GLYCOGEN PHOSPHORYLASE
GLUTATIONE
CYSTATHIONINE
HEME
NIACIN
HISTAMINE
SEROTONINE-GABA-EPI.NOREPI-DOPA

46
Q

BIOTINA COFACTOR DE

A

PYRUVATE CARBOXYLASE (piruvato a oxalacetato)
ACETYL COA CARBOXYLASE (acrtyl coa a malonylcoa)
PROPIONYL COA CARBOXYLASE (propionil coa. A metilmalonic coa)

47
Q

Cobalabina cofactor de que enzimas

A

Metinonine synthase
Methylmalonyl coa mutase

48
Q

Stop codon

A

UAA
UAG
UGA

49
Q

Start codon

A

AUG

50
Q

Promoter of transcription

A

CAAT
TATA

51
Q

Blue esclera

A

Osteogenesis imperfecta
Alkaptonurua