UW 3/6-3/10 not in Firecracker

Question 1

What are some common drugs to avoid in older adults due to increased side effects?

Answer 1

Anticholinergics- (Diphenhyrdamine–> lead to confusion, hallucinations etc)
CNS- TCADs, Antipsychotics, Benzos
Cardiovascular- Most antiarrhythmic
Endocrine- Sliding scale insulin
Pain- Non-Selective NSAIDs, muscle relaxants.

These are Beers Criteria

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Question 2

What does Creatinine kinase measure?

Answer 2

Cellular Damage of Heart, brain, or skeletal muscle.

Question 3

How can you tell the difference between a inferior gluteal and superior gluteal nerve damage?

Answer 3

Inferior=Gluteus Maximus= trouble rising from seated position or climbing stairs (extension and external rotation of the thigh)

Superior=Glut medius, minumus, tensor fasciae latae=Pelvic tilt contralaterally, lean towards lesion while walking.

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Question 4

What is the major thyroid hormone secreted from the thyroid?

Answer 4

T4, which is then converted to T3 and Reverse (inactive) T3.

Question 5

How can you prevent the niacin “flush?” Why does this work?

Answer 5

Administer aspirin because this blocks prostaglandin synthesis

Question 6

A man is administered an IV antibiotic and shortly after begins having a flushed appearance and itching all over his face/neck. What is this called? What molecule mediates this reaction?

Answer 6

Red Mans Syndrome (Vancomycin)

Mediated by Histamine Release.

Question 7

Inhaled cortical steroids function by blocking which Arachidonic acid products?

Answer 7

LTC-4 LTD-4, LTE-4

-Responsible for bronchospasms, vasoconstriction, and inc vascular permeability (mucus secretion into airtways)

Question 8

Review Vitamin Deficiencies here:

Answer 8

Markwell Blog vitamin def.