Uveitis Flashcards
inflammation of the entire uveal tract
panuveitis
inflammatory mediator of uveitis
prostaglandins
prostaglandins affect the ciliary body - cause a decrease in aqueous humor drainage or production?
dec production
prostaglandins cause what IOP
decrease IOP
C/S of Acute uveitis
• aqueous flare in anterior chamber - hallmark of uveitis ◦ protein • cells in anterior chamber • ciliary flush - wbc that instead of settling down at bottom get stuck on corneal endothelium in clumps • corneal edema • blepharospasm - pain (squinting, tearing, rubbing) • lacrimation • hypopyon - wbc in anterior chamber • hyphema • photophobia - miosis - keratic precipitates • iridal swelling
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C/S of chronic uveitis
- cataracts
- synechia
- phthisis bulbi
- rubeosis iridis - preiridal fibrovascular membrane (bv in this membrane make iris look red)
- deep corneal vascularization
- iris bombe - 360 degree posterior synechia –> 2dry glaucoma
- iris pigmentation
- glaucoma
- lens luxation
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Catagories of uveitis causes
bacterial viral fungal protozoa parasites alge immune neoplasia trauma
fungal causes of uveitis
blastomycosis - sub retinal granulomas & 2dry glaucoma
histoplasmosis - cats
cryptococcosis - cats
coccidiomycosis - southwest
Viral causes of uveitis
distemper FIV FeLV FIP - very severe uveitis, dry form adenovirus-1 - blue eye keratouvieitis (corneal edema) endotheleitis equine herpes virus type 1 & 2
bacterial causes of uveitis
lyme
lepto - horses
ehrlichia
rickettsia rickettsii (rocky mountain spotted fever)
brucella canis - intake females (promisquis)
bartonella
rhodococcus equi - foals
protozoal causes of uveitis
toxoplasmosis
leishmania - sand fly
parasite causes of uveitis
oncocerca cervicalis
dirofilaris immitis
alge cause of uveitis
protheca
immune mediated cause of uveitis
lens induced uveitis
uveodermatologic syndrome
immune mediated thrombocytopenia
what is phacolytic LIU
lens proteins leak through intact capsule (fast developing or hyper mature cataracts)
what is phacoclastic LIU
pp. leakage following rupture of lens capsue - cat claw
intraocular neoplasia of the uvea
ciliary body adenoma/carcinoma
uveal melanoma
secondary neoplasia of the uvea
lymphosarcoma most common
hemangiosarcoma
fibrosarcoma
what is reflex uveitis
is initiated by the pain and inflammation associated with corneal ulceration
how do you treat reflex uveitis? what should you not use?
atropine and systemic NSAIDs
do not use topical steroids
what does atropine do?
mydriasis
cycloplegia - paralyzes ciliary muscles (stops spasms)
when can you not use atropine
when secondary glaucoma is a risk - post cataract surgery
what are the 3 main goals of treating uveitis
stop inflammation
dilate pupil
paralyze ciliary body
how often do you a topical NSAID for uveitis
4-6 times a day
