Uveitis Flashcards

1
Q

Still’s Triad

A

Cataract, band keratopathy and Uveitis (chronic)

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2
Q

Flare is usually more noticeable

A

in chronic granulomatous uveitis

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3
Q

Plasmoid aqueous

A

3-4+ Grading flare, Aq is thick and white.
can be seen in severe acute uveitis.
Dense accumulation of fibrin cells producing translucent to cloudy strands or sheets with lumps of protein material

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4
Q

Iris Membranes

A

Uveitis sign

Non-fibrous membranes may come off the collaretes

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5
Q

3 major types type of KP

A

Fine (easy to detect, 3d appearance)
Granulomatous (thick, flat and waxy)
Pigmented

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6
Q

Fine Keratic Precipitates

A

Whitish-gray fibrin or epitheloid cells.

very small and adhere to posterior cornea

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7
Q

Granulomatous Keratic Precipitates

A

Greasy, waxy, grainy-appearing surfaces

looks like mutton fat

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8
Q

Pigmented Keratic Precipitates

A

Arlt’s triangle or Krukenberg’s spindle:
deposit in endothelium as well
With base down and apex up

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9
Q

Hypopion

A

Assoc with severe acute anterior uveitis
dense accumulation of white blood cells
usually PolyMorphoNuclear (PMN) cells
More common in Behcet’s, Leprosy, Endopthalmitis, Sarcoid, and post surgical uveitis
(BLES)

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10
Q

Anterior Synechiae:

A

Peripheral Anterior Synechiae or PAS

Fibrous adhesions between peripheral cornea and iris

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11
Q

Posterior Synechiae:

A

More common than anterior synechiae
Adhesions between the pupillary border and the anterior lens capsule
Form readily in all types of uveitis
Especially in the presence of flare
May occur in conjunction with iris nodules
Sometimes mistaken for persistent pupillary membranes

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12
Q

Seclusio Pupillae

A

Immobile pupil with a 360 posterior synechiae

Usually in chronic uveitis

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13
Q

Iris Nodules

A

Koeppe nodules and Busacca nodules

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14
Q

Koeppe nodules

A

Common in uveitis, round or oval tissue
Located at the pupil border
May accumulate pigment over time

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15
Q

Busacca Nodules:

A

Whitish-yellow lumps away from pupil border

In the internal iris stroma

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16
Q

Henkind test:

A

Shining a light in the non-affected pupil will cause pain in the other (consensual) pupil

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17
Q

iris bombe

A

Fluid build up btw lens and iris

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18
Q

lower iop in early stages is from

A

Due to reduced aqueous production of inflamed ciliary body

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19
Q

IOP may increase

A

Trabecular congestion may reduce outflow

Also consider iatrogenic increase in IOP due to steroid response

20
Q

What types of cataracts are associated with uveitis?

A

Epi-capsular stars
PSC
Mature cataract

21
Q

Cystoid Macular Edema occur if

A

inflammation is chronic

22
Q

Bilateral uveitis suggests you are dealing with which type of uveitis?

A

endogenous and chronic types of uveitis, especially if granulomatous

23
Q

Unilateral uveitis is more common in

A

Sarcoid, Behcet’s, foreign body, post-surgical events

24
Q

When is uveitis considered chronic?

A

Persistent

Tends to relapse less than three months after discontinuing treatment

25
Q

Which chronic diseases cause non-granulomatous uveitis?

A

Juvenile Rheumatoid Arthritis

Fuch’s Heterochromic Iridocyclitis

26
Q

Which chronic diseases cause granulomatous uveitis ?

A
Tuberculosis (get granulomatous elsewhere)
Sarcoidosis
Syphilis 
Cat scratch fever (comes from kittens)
Fungal infections
27
Q

What are the three events that occur in uveitis?

A

inflammation of any of the structures of the uveal tract
Disruption of the blood-ocular barrier
Infiltration of leukocytes and protein leakage

28
Q

Duration and onset of acute Anterior uveitis.

A

Sudden onset
Moderate to severe pain
Duration 6-12 weeks with/without therapy
non-granulomatous disease with fine keratic precipitates (precipitate in endothelium)

29
Q

Non-Caseating Granulomatous

A

hard inside
Chalazion
Epidermoid/dermois cyst
Sarcoidosis

30
Q

Caseating Granulomatous

A

soft cheesy

TB granuloma

31
Q

What are the characteristics of recurrent uveitis

A

Third episode reclassifies patient as recurrent
Requires complete medical evaluation
Repeated episodes with inactivity longer than 3 months

32
Q

Which diseases are heavily associated with males?

A

trauma
ankylosing spondylitis
Reiter’s syndrome

33
Q

Which diseases are heavily associated with females?

A

Granulomatous type double in females due to sarcoidosis
Childhood uveitis greater in females due to
Still’s Disease:

34
Q

Which type of uveitis is most common by race?

A

Blacks: sarcoidosis Especially in black females, Southeastern US.
Asians: Vogt-Koyanagi-Harada Syndrome, Bechet’s disease.
Caucasians: ankylosing spondylitis, Reiter’s syndrome, HLA-B27 diseases

35
Q

Which type of uveitis is associated with Type A personality?

A

Pars Planitis
high stress
trauma with CL wear

36
Q

The release of these chemicals cause the breakdown of the blood aqueous barrier. Which ones are they?

A

Histamine
Bradykinin
Serotonin

37
Q

Which corneal disease causes severe swelling when the patient also has uveitis?

A

Fuch’s endothelial dystrophy

38
Q

Give examples of endogenous causes of uveitis?

A

Pars planitis-Uveitis with snow banks on ora or pars plana.
Fuch’s heterochromic iridocyclytis.
Posner-Schlossman glaucomatocyclitic crisis

39
Q

What is the hallmark finding of pars planitis?

A

Cells and opacities in the vitreous base (critical findings)

40
Q

Elevated IOP
Uni-ocular
Mild idiopathic anterior chamber inflammation

A

Possner-Schlossman Syndrome/ Glaucomatocyclitic Crisis

41
Q

Pain is most likely associated with chronic or acute uveitis?

A

Acute uveitis may be severe and debilitating

Chronic uveitis may be asymptomatic ( sometimes)

42
Q

vision symptoms

A

Acute uveitis: vision is usually normal to hazy

Chronic uveitis: the vision may be worse than the symptoms

43
Q

stromal edema

A

present in “hot” acute anterior uveitis, present with dense KP
Present in advanced and chronic cases

44
Q

Band keratopathy is common in which type of uveitis?

A

Band Keratopathy may develop in recurrent/ advanced or chronic cases

45
Q

Iris Atrophy

A

occurs in chronic uveitis
May produce decrease in iris pigment
Smooth velvety appearance

46
Q

Iris Granulomas

A

may form on the pupil border, anterior surface of the iris or angle locations.
associated with granulomatous disease
common in sarcoid