UTI/Sepsis Flashcards
Most common UTI pathogen
E Coli
Patients at risk for UTI
- Immunosuppressed
- Diabetics
- Multiple courses antibiotic treatment
- Travelled to certain developing countries
Classifications of UTI
Upper vs Lower
Complicated vs Uncomplicated
Tissues of Upper UTI
Renal, urinary pelvis, ureters
Pyelonephritis is an example of an
Upper UTI
Lower Tract UTI have
No systemic manifestation
Examples of lower tract UTI
cystitis, urethritis
Uncomplicated UTI
- Occurs in otherwise normal urinary tract
- Usually involves only the bladder
Complicated UTI
- Those with coexisting presence of:
- Obstruction
- Stones
- Catheters
- Existing diabetes/neurological disease
- Pregnancy-induced changes
- Recurrent infection
Urinary tract above urethra normally:
Sterile
6 Defense mechanisms against UTIs
- Peristaltic activity
- Acidic pH of urine
- High urea concentration
- Abundant glycoproteins
- Complete emptying of bladder
- Ureterovesical junction competence
How are organisms introduced into urinary system
- ascending route of urethra, originates from perineum
- blood stream
- lymphatics
2 General Predisposing Factors to UTI
- factors that increase urinary stasis
- foreign bodies
Clinical Manifestations of UTI
- Urinary frequency
- > every 2 hours
- Urgency
- Incontinence
- Nocturia
- Nocturnal enuresis – bed wedding
- Pain on voiding/Dysuria
- Retention (also promotes UTI)
Symptoms indicating upper tract UTI
SYSTEMIC
Flank pain, chills, and fever
What are the symptoms of UTI when bacterial count is high?
Symptoms may be nonspecific (ie: fatigue) when bacterial counts high
Clinical Manifestations of UTI in older adults
- Symptoms are often absent
- Experience nonlocalized abdominal discomfort rather than dysuria
- May have cognitive impairment
- Are less likely to have a fever
Diagnostic Studies for UTI
- history/physical exam
- urinalysis
- culture and sensitivity
- CT
- Pyelogram
Course of ABX for uncomplicated cystitis
short-term course (1 to 3 days)
Course of ABX for complicated UTIs
Require long-term treatment (7 to 14 days)
Trimethoprim/sulphamethoxazole (TMP/SMX) use
Uncomplicated/initial UTI
assess for sulfa allergy
Nitrofurantoin use
Long term UTI
Fluroquinolone use
Complicated UTI
Health History for UTI
- Previous UTIs, calculi, stasis, retention, pregnancy, STIs, bladder cancer
- Use of antibiotics, anticholinergics, antispasmodics
- Urological instrumentation
- Urinary hygiene
- Other infections – ex: fungal
- N/V, anorexia, chills, nocturia, frequency, urgency
- Suprapubic/lower back pain, bladder spasms, dysuria, burning on urination