Uterus

Question 1

GOG 33:

Summary

Answer 1

Surgicopathologic factors for LN spread.

1. DOI, grade, LVSI
2. Cytology, adnexal disease, intraperitoneal disease

*DOI, grade, and intraperitoneal disease were independent risk factors.

• G1 disease 3-11% LN positive
• G3 disease 18-34% LN positive

Question 2

GOG 33:

Stage 1 cancers

Answer 2

9% pelvic nodes positive
6% para-aortic nodes positive
5% adnexal involvement
6% extrauterine metastasis