Uterus Flashcards
Uterine contraction
Alpha 1adreno R agonist
Oxytocin R agonist
Prostaglandins
A1 adrenoceptor agonist
Use and ADEs
Ergometrine- sustained uterine contraction for long periods
Used in post party Mum hemorrhage and prevention
Nausea and vomiting
Hypertension
Oxytocin
ADE
Induction of Labour
ADE
N/V
Water retention by inappropriate adh action
Heat stable oxytocin
Carbetocin
Prostaglandins
2
Dionoprostone - labour induction
Carboprost- pp.h when both ergometrine and oxytocin fail
Uterine Relaxants
B2 adrenoceptors Oxytocin antagonist COX inhibitor- non selective NO Ca c blocker Mg Sulphate
COX inhibitor
Indomethacin
P o A < 32 weeks
B2agonist
Salbutamol
Terbutaline
Ritodrine
Tachycardia and hypokalemia
Mg SO4
Neuromuscular blocker, ca channel blocker
For eclampsia
Teratogenic and ADE arrhythmia - 2/3rd line drug
Oxytocin Antagonist
Atosiban
Ca channel blocker
Oral Nifedipine
No serious ADEs- hypotension