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QBank Double misses > USMLE World 2x misses > Flashcards

USMLE World 2x misses Flashcards

1
Q

Vitamin D deficient rickets shows what in the bone

A

Osteoid matrix accumulation around trabeculae

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2
Q

order of enzymes in base exision repain

A

glycosylase, Endonucleoase, lyase, DNA polymerase, ligase

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3
Q

auer rods indicate

A

AML

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4
Q

antibiotics for beta lactamase producing gram - rods

A

piperacillin-tazobactam

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5
Q

enzyme that allows bacteria to incorprate RNA primers into their DNA during replication

A

primase

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6
Q

deficient enzyme in porphyria cutenea tardea

A

uroporphyrin decarboxylase

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7
Q

sun blistering porphyria

A

cutenea tardea

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8
Q

antiviral reverse transcripterase/DNA polymerase inhibitor that does NOT require intracellular activation by viral/cellular kinases (works in vitro)

A

foscarnet

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9
Q

collegen defect with soft and loose skin with mutile acchymoses on limbs, and hypermobile joints

A

ehlers danos

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10
Q

collegen sensitive step impaired in ehlers Danlos

A

extracellular cleavage

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11
Q

endogenous substances that can lead to insuline resistance by abberent serine and theonine phosphorylation by serine kinase

A

TNF-a, catecholamines, glucocorticoids and glucagon

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12
Q

Side effects of ACEi

A

decreased GFR, hyperkalemia, cough

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13
Q

BP med that can cause angioedema

A

ACE inhibitor

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14
Q

carries nerves and vessels to ovaries

A

suspensory ligament

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15
Q

crystals that cause gout

A

monosodium urate

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16
Q

Tx for diptheria infection

A

passive immunization (diptheria antitoxin), is the most important thing to do

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17
Q

kid with blast cells in blood, with mediastinal mass

A

most likely T-Cell ALL (B cell is more common ALL, but does not make mass

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18
Q

anticoagulanr that can rarely cause neutropenia in long term

A

ticlopadine

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19
Q

ceremide trihexoside accumulation leads to

A

Fabry dx (causes renal failure). deficiency of alpha-galactosidase A

20
Q

most important tx in acute diptheria infection

A

antitoxin (passive immunity)

21
Q

nonradiolucent kidney stones is probably made up of

A

uric acid

22
Q

tazobactam increases the efficacy of amoxicillin by…

A

decreasing beta-lactamase production by the bug, increasing avaiability of beta-lactam drug itself

23
Q

breaks down blood in a bruise, and turns it green

A

heme oxygenase

24
Q

CD markers in B-ALL

A

TdT+. CD10+, CD19+ (T-cell would all be less than 10)

25
Q

ehlers danos presents as

A

hypermobile jonts, easy bruising, hyperelastic skin

26
Q

collegen processing defect in ehlers danos

A

extracellular cleavage (

27
Q

causes one sided nasal hemianopia

A

lesion in right peri-chaismal area (often anyrusm or calcification in internal carotid)

28
Q

kidney risk in hysterectomy

A

uterer can be accidently ligated along with the uterine artery

29
Q

anti cholesteral med that can raise TGs

A

cholestyramine

30
Q

secretes hydrogen from intercalated cells of the collecting tubules

A

aldosterone

31
Q

effect of aldosterone on the nephton

A

causes reabsorption of sodium and water and loss of K+ and H+

32
Q

homologous chromosomes seperate in what phase of meosis

A

mesosis I

33
Q

relationship between lumen radius loss and flow change

A

flow change is loss of lumen to the 4th (i.e. i/2 loss of lumen = 16x loss of flow)

34
Q

pioglitazone can damamge what orgon

A

liver

35
Q

combo of AZR and gangicilor can cause

A

neutropenia

36
Q

loss to followup in studies can create what bias

A

selection

37
Q

alkaptonuria (black urine dx) blocks what

A

tyrosine (from phenalyline) to fumerate (needed for TCA cycle)

38
Q

viruses that can undergo gentic reassortment when exposed to aminal orthomyxovirues

A

flu and rotovirus

39
Q

inactivates 6-mercaptopurine

A

xanthanine oxidase

40
Q

used to treat cyanide poisoning in nitrate OD

A

sodium thiosulfate

41
Q

QRS complex corresponds to what phase in ventricular AP graph

A

0 phase

42
Q

what happens in the 0 phase of ventriculat AP

A

rapid, Na mediated deporalization

43
Q

what drugs modulate the 0 phase of ventricular depolarixation

A

class I antiarrythmics (slow Na inward movememt)

44
Q

used to control acute PSVT

A

adenosine

45
Q

SE of adenosine

A

flusing, burning in chest and SOB

QBank Double misses (1 decks)

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