USMLE 1

Question 1

Respiratory depression and miosis in an unresponsive patient strongly suggests:
Treated with:

Answer 1

Opioid overdose, treated with naloxone, an mu receptor competitive

Question 2

Metoprolol MOA

Answer 2

B-1-adrenergic receptor inhibitor

Question 3

Hibernating miocardium

Answer 3

characterized by persistently impaired myocardial contractility at rest that is partially or completely reversible when adequate oxygen supply is restored

Question 4

Glucagon injection

Answer 4

Activates adenylyl cyclase that promotes gluconeogenesis and glucogenolysis

Question 5

Injection of an autoclaved microorganism

Answer 5

Lepromin test

Question 6

Multiple myeloma

Answer 6

Kahler disease is a malignant plasma dyscrasia (abnormal proliferation of the same type of plasma cell that may secrete a monoclonal immunoglobin) in the bone marrow

Question 7

Hypokalemia manifestations

Answer 7

Fatigue, weakness, hyporeflexia and ECG of T-wave flattering

Question 8

Insulin in potassium

Answer 8

Promotes transport of potassium from the bloodstream into cells

Question 9

Costocondritis caused by

Answer 9

excercise or chest wall trauma

Question 10

Testicular tumor markers

Answer 10

AFP (Alpha-fetoprotein)
HCG (Human chorionic gonadotropic)
LDH (Lactate dehydrogenase)

Question 11

Warfarin MOA

Answer 11

is a (vitamin K) antagonist which acts to inhibit yhe production of vitamin K by vitamin K expoxide reductase

Question 12

Propanolol

Answer 12

is a nonselective B-adrenergic receptor antagonist

Question 13

Citalopram

Answer 13

inhibits the CNS neuronal reuptake of serotonin

Question 14

Trazodone

Answer 14

inhibit the reuptake of serotonin and block both histamine and alpha-1-adrenergic receptors

Question 15

Priapism definition

Caused by which drug

Answer 15

sustained erection that lasts for more than four hours and is not the result of sexual erection.
Potential side effect of trazodone

Question 16

PDGR (platalet-derived growth factor)

Answer 16

stimulating the proliferation and migration of smooth muscles cells in the trauma intima

Question 17

Paradoxical embolism definition and association

Answer 17

when an embolus passes through a shunt into arterial circulation and causes end-organ infarction.
Associated with ADS and PFO
Atrial septal defects and patent foramen ovale