Using Genome Projects

Question 1

What is the genome?

Answer 1

The complete set of genetic information contained in the cells of an organism

Question 2

What is genome sequencing?

Answer 2

Identifying the DNA base sequence of an individual. This allows us to determine the amino acid sequence of the polypeptides coded for by that DNA

Question 3

What is the proteome?

Answer 3

The complete set of proteins that can be produced by a cell

Question 4

Give an application of sequencing the proteome in simple organisms

Answer 4

Identifying potential antigens for use in vaccine production

Question 5

Give (some) applications of genome sequencing

Answer 5

• Comparing genomes between species to determine evolutionary relationships
• Genetic matching
• Personalised medicine
• Synthetic biology

Question 6

How have sequencing methods changed over time?

Answer 6

Used to be manual process, however now it has become automated. A reaction mixture is created and after the process if complete, a machine reads the base sequence