Urology Flashcards
prostatitis
acute causes
caused by staphylococcus faecalis and E. coli, chlamydia and TB
prostatitis
acute features
UTIs
retention
haematospermia
swollen/ boggy prostate on DRE
prostatitis
actue treatment
analgesia
levofloxacin 500mg/day PO for 28/7
Prostatitis
Chronic
bacterial or non-bacterial
symptoms same as acute >3/12
Doesn’t respond to abx
anti-inflammatory drugs, alpha blockers and prostatic massage
Balantitis
acute inflammation of foreskin and glans
associated with strep and staph infections
more common in diabetics
often seen in children with tight foreskins
Rx - abx, circumcision, hygiene advice
Phimosis
foreskin occludes meatus
causes recurrent balantitis and ballooning
time and trials of retraction may prevent need for circumcision
in adults - painful intercourse, infection, ulceration and associated with balantitis xerotica obliterans
Paraphimosis
tight foreskin retracted and becomes irreplaceable
–> prevents venous return –> oedema and ischaemia of the glans
Rx –> ask pt to squeeze glans, glucose soaked swab, ice pack, lidocaine
–> may need aspiration, dorsal slit/ circumcision
Prostate Ca
commonest male cancer
increasing incidence with age
associated with positive family hx
mostly adenocarincoma arising in peripheral prostate
Symptoms of prostate Ca
asymptomatic nocturia hesitancy poor stream terminal dribbling obstruction weight loss +/- bone pain suggests mets
DRE of prostate in Ca
hard irregular prostate
Diagnosis of Prostate Ca
raised PSA transrectal USS & biopsy X-rays bone scan MRI/CT
Treatment of Prostate Ca
Disease confined to prostate
- radical prostatectomy
- radical radiotherapy +/- neoadjuvant & adjuvant hormonal therapy
- hormone therapy alone - delays disease progression
- active surveillance
Treatment of Prostate Ca
Metastatic Disease
- hormonal drugs - LHRH agonists goserelin stimulate and then inhibit pituitary gonadotrophin
Symptomatic treatment of Prostate Ca
analgesia
treat hypercalcaemia - fluids and allopurinol
radiotherapy for bone mets/ spinal cord compression
Penile Ca
rare in the UK - more common in Far East and Africa
very rare if circumcised
related to chronic irritation, viruses and smegma
Presentation: chronic, fungating ulcer, bloody/ purulent discharge - 50% spread to lymph at presentation
radiotherapy if early, amputation and lymph node dissection if late .
Benign Prostatic Hyperplasia
Pathology
benign nodular or diffuse proliferation of musculofibrous and glandular layers of the prostate
inner (transitional) zone enlarges in contrast to peripheral layer (vice versa in prostate Ca)
Benign Prostatic Hyperplasia
Features
lower urinary tract symptoms
- nocturia, frequency, urgency, post-micturition dribbling, poor stream/ flow, hesitancy, overflow incontinence, haematuria, bladder stones, UTI
Benign Prostatic Hyperplasia
Tests
MSU U&E USS Rule out Ca- PSA Transrectal USS +/- biopsy
Benign Prostatic Hyperplasia
Lifestyle Management
Avoid caffine/ alcohol
relax when voiding
void twice in a row to aid emptying
control urgency by practicing distraction methods
train bladder by holding on to increase time between voids.
Benign Prostatic Hyperplasia
Drugs - alpha blockers
(tamulosin, alfuzosin, doxasosin, terazosin) decrease smooth muscle tone (prostate and bladder)
SE: drowsiness, depression, dizziness, low BP, dry mouth, ejaculatory failure, extra-pyrimidal signs, nasal congestio, increased weight
Benign Prostatic Hyperplasia
Drugs - 5alpha-reductase inhibitors
e.g. finasteride - decrease testosterone’s conversion to dihydrotestosterone
- excreted in semen so advice to use condoms, women should avoid handling
SE - impotence, low libido
Benign Prostatic Hyperplasia
Surgery
Transurethral resection of the prostate
Transurethral incision of the prostate- relieves pressure on urethra
Retropubic prostatectomy
Transurethral laser-induced prostatectomy
Acute Retention
Causes
Bladder usually tender (+600ml)
causes - prostatic obstruction, urethral strictures, anticholinergics, alcohol, constipation, post-op, infection, carcinoma, neurological
Acute Retention
MAnagement
- analgesia, privacy, running taps, hot bath
- alpha blocker
clot–> 3 way catheter and washout
catheter and then TWOC
Acute Retention
Prevention
Finasteride to decrease proste size and retention risk
tamulosin reduces risk of recatheterisation
Chronic Retention
Presentation
more insidious and maybe painless
Overflow incontinence
acute on chronic retention
lower abdo mass
UTI or renal failure
Chronic Retention
Causes
Prostatic enlargement Pelvic Malignancy Rectal Surgery DM CNS disease- transverse myelitis/MS
Chronic Retention
Management
Avoid catheterising unless pain/UTI or renal impairment
Institute definitive treatment promptly
Intermittent self-catheterisation may be needed
Epididymal Cysts
develop in adulthood
contain clear/milky fluid - spermatocele fluid
lie above and behind testis
remove if symptomatic
Hydrocele
fluid in the tunica vaginalis
primary- patent processus vaginalis–> common, larger, younger
secondary- trauma/ infection/ tumour
Rx - aspiration or surgery
Epididymo-orchitis
Causes
chlamydia e.coli mumps (EBV) n. gonorrhoea TB
Epididymo-orchitis
features
sudden onset tender swelling
dysuria
sweats/ fever
Epididymo-orchitis
investigations
1st catch urine sample
look for urethral discharge
consider STI screen
ward of possible infertility, symptoms may worsen before improving
Epididymo-orchitis
Management
<35 doxycycline (treat sexual partners) (if suspect gonorrhoea –> add ceftriaxone)
> 35 (non-STI) ciprofloxacin or ofloxacin
ALSO: analgesia, scrotal support, drainage of abscess