Urology Flashcards
evaluation and tx of urinary retention
- Placement of foley catheter and UA
- Imaging indicated only if infection or stones suspected
- Patients d/c home with foley in place, urology follow up (leave in w/ BPH, post surgery)
- NO ABX UNLESS HIGH RISK
- consider alpha adrenergic blockers (tamsulosin) after urologist consult (postural hypotension)
how do you get a clean UA sample w/ a woman on her period?
quick in and out cath to prevent tampon/blood contamination
__% of females and ___% of males will experience kidney stones
5% F
12% M
3:1 M:F
contraindications for IVPs
- allergy (0.1%) affected,
- DM
- RI creatinine over 1.8
- dehydration
- multiple myeloma
- patients on glucophage (fatal metabolic acidosis)
tx of intestital nephritis/renal ARF
- Discontinue the offending drug
- Self limited if recognized early, may require brief dialysis
- Corticosteroids
how do you dx pyelonephritis
- CVA tenderness
- UA: dip will show protein, LE, nitrites
- Micro: WBC’s bacteria, WBC casts,
- Urine Cx +
- CBC: leukocytosis with left shift
medical tx for kidney stones
Calcium oxalate stones: Hypercalciuria: thiazide diuretic + potassium citrate
Uric acid stones:
- Increase urine pH to 6.5-7.0
- Potassium Citrate
- Allopurinol
presentation of acute cystisis
- Dysuria
- Frequency
- Urgency
- Suprapubic pain
- Hematuria- Amount of blood in urine is NOT proportional to the size of the stone
- Low grade fever
sudden and severe drop in blood pressure (shock) or interruption of blood flow to kidneys from severe injury or illness
pre-renal ARF
PE findings of ARF
- Look for evidence of either hypovolemia (tachycardia, orthostatic VS, decreased skin turgor)
- Hypervolemia (S3, JVD, edema, rales)
- Percuss the bladder ( percussable with 150 ml, palpable with 500 ml urine)
- U/S can tell you how much urine is in bladder
what causes staghorn calculi
struvite stones
what type of kidney stones do not cause pain?
intra-renal stones (actually in the kidney or bladder)
urinalysis and urine culture findings w/ renal colic and their associated ddx
- hematuria- does not correlate w/ % of obstruction- inflammation (ie. appendicitis)
- pyuria– inflammation or bacteriuria infection
- crystals– may correspond to stone type
- pH over 7.6– proteus infection or Renal tubular acidosis (RTA)
what are the 3 mechanism of ARF
- preprenal (50%) – perfusional/shock
- intrarenal–glomerular, tubular, interstitial
- postrenal– obstructive
*Usually rule out pre and post renal before considering the many intrinsic causes
dx of prerenal AFR
- Urine spec grav over 1.030- (concentrated)
- Serum Bun/Creatinine over 20
- Urine osmolality over500 (H)
- FENA less than 1
PE findings of kidney stones
- Vitals: tachy, HTN, tachypnea, diaphoresis (if hypotensive be concerned)
- fever– stone that is secondarily infected
- flank tenderness, CVA tenderness
- Abdominal tenderness but without peritoneal signs. Pain should not be exacerbated with exam. (NO POINT TENDERNESS)
- BS hypoactive
- IMPORTANT TO ASCULATE FOR BRUITS
describe when each procedure is indicated:
- ESWL (extracorporeal shock wave therapy)
- Percutaneous Nephrolithotomy
- renal stents
- ureteroscopy
- ESWL (extracorporeal shock wave therapy)- for renal stones less than 2cm
- Percutaneous Nephrolithotomy- renal stones over 2cm or proximal ureteral stones less than 1cm
- renal stents
- ureteroscopy- distal ureteral stones
tx of glomerulonephritis/ renal ARF
- high dose corticosteroids,
- possible exchange transfusions until chemotherapy.
tx of chronic renal failure
- Good management of underlying condition (ie. good control blood sugars)
- Dialysis
- Transplantation
struvite stones/staghorn calculi requires what type of environment?
pH greater than 7.2 and ammonia (caused by UTIs) Proteus is the most common organism
what does IVP evaluate?
- evaluates renal function
- it visualizes the entire urinary tract
- assesses the function of the kidney
- degree of obstruction
a stone must be how big to show up on a KUB image
2mm
when is flomax less helpful in kidney stones?
- smaller stones
- ppl with hypotension
clinical presentation of kidney stones
- severe renal colic on affected side
- pt constantly moving trying to find a position of comfort
- visceral pains (caused by distention of the ureter)
- N/V
*not typically shocky– if hypotensive think about other things
does cranberry juice help with UTIs?
- Cranberry Juice contains 3 proanthocyanidin chemical compounds which prevent the adherence of E. coli to the uroepithelial cells.
- 200-750 ml of juice or daily cranberry tablets may reduce infection by up to 20%
*but very sugary!!
struvite stones/staghorn calculi is most commonly seen with what?
FB in urinary tract and neurogenic bladder
*proteus is the most common organism
most common microscopic finding w/ pyelonepthritis
WBC casts
what is the tx for UTIs
- 7 day course of nitrofuratoin 100mg BID in women (7 day course in children and men too)
- 3 day oral coures of TMP/SMZ (have increasing resistance patterns)
- Fosomysin (monurol) 3g oral ($$)
- increase fluids
- Urinary tract analgesic (phenazopyridine)
- longer course (7-10 days) in preg, DM, elderly recurrences
what is acute renal failure
Sudden decrease in Renal function resulting in an inability to maintain fluid and electrolyte balance and excrete nitrogenous wastes
- Failure is defined as a 2-3 fold increase in serum creatinine +/- a decrease in urine out put of less than 5 cc/kg/hr for 24 hours
- serum creatinine is most useful marker
what group of people are at greatest risk for kidney stones
- 70% between 20-50y/o
- Caucasians (rare in AA and NA)
dx of intestital nephritis/renal ARF
Diagnosis: fever, azotemia, rash, arthralgias
Urine micro: pyuria, esp. eosinophiluria**, WBC casts, hematuria
renal biopsy*
what do these casts typically suggest?
- WBC casts
- Muddy brown casts
- Red cell casts
WBC casts= pyelonephritis or interstitial nephritis/renal ARF
Muddy brown casts= Acute tubular necrosis
Red cell casts= glomerulonephritis
Calcium Oxalate stone are associated w/ what?
- hypercalcemia from primary hyperparathyroidism
- hypercalciuria
- malignancy
- sarcoid
- hyperoxaluric states (a lot of sweet tea) from:
- Crohns
- Jejunal ileal bypass
- small bowel disease
what meds can cause urinary retention?
- anti-cholinergic medications (w/ BPH and strong anti-emetic),
- antihistamines
- ephedrine and amphetamines
____ may cause hydronephrosis due to compression, and hematuria (ureteral irritation)
rupturing AAA
dx of glomerulonephritis/ renal ARF
Dependent edema and hypertension
UA shows red cell casts
pros of helical CT for kidney stones
- Fast, no contrast
- IDs the stone anywhere along the GU tract
- accurately sizes the stone
- Hounsfield typing may differentiate type of stone, less than 400 consistent with uric acid
- May give information about other intra-abdominal structures (AAA, mass)
SE of of phenazopyridine
Urinary tract analgesic– stains tears (no contacts) and urine
why are NSAIDs beneficial for renal colic
- non-sedating
- no ureteral spasm
- no effects on hemodynamics
*keterolac (Toradol) or diclofenac most widely used
prior to all radiation tests (ie. CT) think about what type of study for females?
serum pregnancy test
common causes of urinary retention
- usually secondary to obstruction (ie. prostate BPH or post-op)
- women: MS**, UTI (spasm), prolapse of bladder/rectum/or uterus
- medications
risk factors for renal artery embolus
- embolic diseases
1. Afib
2. PVD
3. IVDU
ARF renal causes
- ATN (acute tubular necrosis) (85%)– from ischemia or toxin
- Interstitial Nephritis (10-15%)
- Glomerulonephritis (5%)
acute inpatient tx of pyelonephritis
- Child, pregnant pt, acutely ill
- IV abx usually ampicillin and Gentamycin to start
- Consider follow up C&S