Urology Flashcards
Alpha1 adrenergic blockers
Relax the smooth muscles of the bladder neck and the prostate capsule and inhibits hypertrophy of these tissues
Useful in treating urinary retention
Alpha 1 adrenergic blockers
Selective TSA: Are specific and have less side effects -Tamsulosin - Silodosin - Alfuzosin
Non selective PDT
- Prazosin
- Docazosin
- Terazosin
Alpha1 adrenergic side effects
DIZZINESS ●POSTURAL HYPOTENSION ●HEADACHE ●RHINITIS or nasal congestion ●DECREASED EJACULATION ●ASTHENIA abnormal physical weakness or lack of energy. ●OTHERS: RAre
5 alpha reductase inhibitors
Shrinks an enlarged prostate gland in order to prevent urinary retention and improved the flow of urine. These drugs block the conversion of testosterone to dihydrotestosterone. No DHT no prostate gland emlagement
Eg: Finasteride: proscar, propecia
Episteride
Dutasteride : completely inhibits both isomer 1(20%) and 2(80%): avodart
5 alpha reductase inhibitors
LOSS/REDUCED LIBIDO
●EJACULATORY DISORDER
●ERECTILE DYSFUNCTION
●GYNAECOMATIA
Phosphodisterase 5 inhibitors
Relaxes the smooth muscle of the bladder neck for the patient to urinate
Enhances prologed erection
Controls BP
Eg: Sildenafil (Viagra) Tadalafil (Cialis) Verdenafil Avanafil Lodenafil
Phototherapy
Plant derived medication that are used to treat and manage UT symptoms Eg: Prostacure Prostamax Prostacare Prostafit
DRE in prostate cancer
- rectal mucosa is fixed
- consistency is hard
- median sulcus is obliterated
- prostate shrinks due to anaplastic tumor
- Ill defined edges
DRE for BPH
- rectal mucosa is flexible
- consistency is firm
- median sulcus is palpable and prostrate symmetrical
- prostate is enlarged
- well defined edges
Exclusion criteria IPSS
- people in urethral catheter will be relieved of all the four voiding symptoms since the catether will remove all
- when symptoms have not lasted for thirty days
Obstructive or voiding symptoms
WISE Weak or poor stream Intermittency Straining Incomplete emptying of the bladder
Irritative and storage symptoms
FUN
- Frequency
- Urgency
- Nocturia
Appendages around the urethra
- seminal vesicles
- epididymis
- prostate
- testes
Organs around the prostate
- seminal vesicles: hemospermia
- rectum: constipation
- lumbar vertebrae: causes low back pain, para- paresis/ plegia(if compressing the nerve root)
Urethra: urinary retention
Urethral stricture hx
- age: less than 50 years old
- pc : difficulty in voiding 3-6 months duration
Hpc: Do you have splitting or forked stream when urinating
Have you had any discharge from your penis in the past? How many years ago
Have you had an STI ( gonococcal urethritis) 8to 15 years ago likely to develop urethral stricture
Does straining improve stream when urinating
Is there are a decrease in the width of your stream
Has a catheter being passed through your urethra or suprapubic region? Are you still having the catether
Have you had a trauma to your pelvis or pelvic fracture
Have you had a straddle injury
Are you able to urinate now